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Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-4769
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dc.contributor.authorRandall, Matthew J.-
dc.contributor.authorJüngel, Astrid-
dc.contributor.authorRimann, Markus-
dc.contributor.authorWuertz-Kozak, Karin-
dc.date.accessioned2018-11-26T15:49:24Z-
dc.date.available2018-11-26T15:49:24Z-
dc.date.issued2018-10-31-
dc.identifier.issn2296-4185de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/13235-
dc.description.abstractThe relevance for in vitro three-dimensional (3D) tissue culture of skin has been present for almost a century. From using skin biopsies in organ culture, to vascularized organotypic full-thickness reconstructed human skin equivalents, in vitro tissue regeneration of 3D skin has reached a golden era. However, the reconstruction of 3D skin still has room to grow and develop. The need for reproducible methodology, physiological structures and tissue architecture, and perfusable vasculature are only recently becoming a reality, though the addition of more complex structures such as glands and tactile corpuscles require advanced technologies. In this review, we will discuss the current methodology for biofabrication of 3D skin models and highlight the advantages and disadvantages of the existing systems as well as emphasize how new techniques can aid in the production of a truly physiologically relevant skin construct for preclinical innovation.de_CH
dc.language.isoende_CH
dc.publisherFrontiers Research Foundationde_CH
dc.relation.ispartofFrontiers in Bioengineering and Biotechnologyde_CH
dc.rightshttp://creativecommons.org/licenses/by/4.0/de_CH
dc.subject3D tissue modelde_CH
dc.subjectBiofabricationde_CH
dc.subjectBioprintingde_CH
dc.subjectElectrospinningde_CH
dc.subjectIn vitrode_CH
dc.subjectPreclinical testingde_CH
dc.subjectSkinde_CH
dc.subjectSkin diseasede_CH
dc.subject.ddc610: Medizin und Gesundheitde_CH
dc.subject.ddc660.6: Biotechnologiede_CH
dc.titleAdvances in the biofabrication of 3D skin in vitro : healthy and pathological modelsde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
dc.identifier.doi10.21256/zhaw-4769-
dc.identifier.doi10.3389/fbioe.2018.00154de_CH
dc.identifier.pmid30430109de_CH
zhaw.funding.euNode_CH
zhaw.issue154de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.start154de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume6de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.webfeed3D Gewebe und Biofabrikationde_CH
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Randall, M. J., Jüngel, A., Rimann, M., & Wuertz-Kozak, K. (2018). Advances in the biofabrication of 3D skin in vitro : healthy and pathological models. Frontiers in Bioengineering and Biotechnology, 6(154), 154. https://doi.org/10.21256/zhaw-4769
Randall, M.J. et al. (2018) ‘Advances in the biofabrication of 3D skin in vitro : healthy and pathological models’, Frontiers in Bioengineering and Biotechnology, 6(154), p. 154. Available at: https://doi.org/10.21256/zhaw-4769.
M. J. Randall, A. Jüngel, M. Rimann, and K. Wuertz-Kozak, “Advances in the biofabrication of 3D skin in vitro : healthy and pathological models,” Frontiers in Bioengineering and Biotechnology, vol. 6, no. 154, p. 154, Oct. 2018, doi: 10.21256/zhaw-4769.
RANDALL, Matthew J., Astrid JÜNGEL, Markus RIMANN und Karin WUERTZ-KOZAK, 2018. Advances in the biofabrication of 3D skin in vitro : healthy and pathological models. Frontiers in Bioengineering and Biotechnology. 31 Oktober 2018. Bd. 6, Nr. 154, S. 154. DOI 10.21256/zhaw-4769
Randall, Matthew J., Astrid Jüngel, Markus Rimann, and Karin Wuertz-Kozak. 2018. “Advances in the Biofabrication of 3D Skin in Vitro : Healthy and Pathological Models.” Frontiers in Bioengineering and Biotechnology 6 (154): 154. https://doi.org/10.21256/zhaw-4769.
Randall, Matthew J., et al. “Advances in the Biofabrication of 3D Skin in Vitro : Healthy and Pathological Models.” Frontiers in Bioengineering and Biotechnology, vol. 6, no. 154, Oct. 2018, p. 154, https://doi.org/10.21256/zhaw-4769.


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