Dynamic intraligamentary stabilisation for the treatment of the anterior cruciate ligament rupture : a health technology assessment for Switzerland

Hess, Sascha; Brunner, Beatrice; Mattli, Renato; Brügger, Urs; Eichler, Klaus

Publication type:	Conference poster
Type of review:	Peer review (abstract)
Title:	Dynamic intraligamentary stabilisation for the treatment of the anterior cruciate ligament rupture : a health technology assessment for Switzerland
Authors:	Hess, Sascha Brunner, Beatrice Mattli, Renato Brügger, Urs Eichler, Klaus
Conference details:	12th Health Technology Assessment international HTAi Annual Meeting, Oslo, Norway, 13-17 June 2015
Issue Date:	2015
Language:	English
Subject (DDC):	362: Health and social services
Abstract:	Background: In addition to current standard therapies (primary operative ACL reconstruction [pOP], primary conservative treatment with possible delayed ACL repair [pKONS]), a new therapeutic option (dynamic intraligamentary stabilisation [DIS]) has emerged. Objectives: To assess patient benefits and costs of DIS compared to standard therapies (pOP, pKONS) in Switzerland. Methods: A decision tree was developed to analyse cost-effectiveness over two time horizons (2 and 15 years). We performed a literature search for effectiveness and safety outcomes in electronic databases. Effectiveness data were pooled with meta-analysis, where suitable. Direct medical costs and productivity losses were calculated in Swiss Francs (year 2012) using clinical expert information and administrative databases. Results: DIS showed to be at least as effective as the comparators. The ratio of patients at 2 years with equivalent sports level as pre-injury was 49% (95%-CI: 36%-66%) for DIS, 39% (18%-82%) for pOP and 36% (26%-51%) for pKONS. The frequency of safety events was similar for the three strategies. Total costs at 2 years were 21’700 CHF for DIS, 26’000 CHF for pOP and 17’000 CHF for pKONS. Sensitivity analyses did not lead to significantly different conclusions. Conclusions: DIS has the potential to be a valuable treatment option for ACL rupture. However, data is scarce and studies with rigorous design and longer follow-up should be performed.
URI:	https://digitalcollection.zhaw.ch/handle/11475/17001
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	School of Management and Law
Organisational Unit:	Winterthur Institute of Health Economics (WIG)
Appears in collections:	Publikationen School of Management and Law

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Hess, S., Brunner, B., Mattli, R., Brügger, U., & Eichler, K. (2015). Dynamic intraligamentary stabilisation for the treatment of the anterior cruciate ligament rupture : a health technology assessment for Switzerland. 12th Health Technology Assessment International HTAi Annual Meeting, Oslo, Norway, 13-17 June 2015.

Hess, S. et al. (2015) ‘Dynamic intraligamentary stabilisation for the treatment of the anterior cruciate ligament rupture : a health technology assessment for Switzerland’, in 12th Health Technology Assessment international HTAi Annual Meeting, Oslo, Norway, 13-17 June 2015.

S. Hess, B. Brunner, R. Mattli, U. Brügger, and K. Eichler, “Dynamic intraligamentary stabilisation for the treatment of the anterior cruciate ligament rupture : a health technology assessment for Switzerland,” in 12th Health Technology Assessment international HTAi Annual Meeting, Oslo, Norway, 13-17 June 2015, 2015.

HESS, Sascha, Beatrice BRUNNER, Renato MATTLI, Urs BRÜGGER und Klaus EICHLER, 2015. Dynamic intraligamentary stabilisation for the treatment of the anterior cruciate ligament rupture : a health technology assessment for Switzerland. In: 12th Health Technology Assessment international HTAi Annual Meeting, Oslo, Norway, 13-17 June 2015. Conference poster. 2015

Hess, Sascha, Beatrice Brunner, Renato Mattli, Urs Brügger, and Klaus Eichler. 2015. “Dynamic Intraligamentary Stabilisation for the Treatment of the Anterior Cruciate Ligament Rupture : A Health Technology Assessment for Switzerland.” Conference poster. In 12th Health Technology Assessment International HTAi Annual Meeting, Oslo, Norway, 13-17 June 2015.

Hess, Sascha, et al. “Dynamic Intraligamentary Stabilisation for the Treatment of the Anterior Cruciate Ligament Rupture : A Health Technology Assessment for Switzerland.” 12th Health Technology Assessment International HTAi Annual Meeting, Oslo, Norway, 13-17 June 2015, 2015.