Biotechnological development and biological activity of Balkan endemic Sideritis scardica Griesb.

Danova, Kalina; Wolfram, Evelyn; Pedrussio, Simona; Koleva, Petya; Aneva, Ina; Evstatieva, Luba

doi:10.1055/s-0037-1608366

Publication type:	Conference poster
Type of review:	Peer review (abstract)
Title:	Biotechnological development and biological activity of Balkan endemic Sideritis scardica Griesb.
Authors:	Danova, Kalina Wolfram, Evelyn Pedrussio, Simona Koleva, Petya Aneva, Ina Evstatieva, Luba
DOI:	10.1055/s-0037-1608366
Published in:	Planta Medica International Open
Volume(Issue):	4
Conference details:	65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017
Issue Date:	2017
Publisher / Ed. Institution:	Thieme
ISSN:	2509-6656
Language:	English
Subject (DDC):	572: Biochemistry 580: Plants (Botany) 660.6: Biotechnology
Abstract:	In vitro culture of Balkan endemic medicinal plant Sideritis scardica was previously initiated and different approaches for influencing the productivity of polyphenolics have been applied [1]. The present work discusses the spectrophotometric and HPTLC phenolics and flavonoids phytochemical profiling, DPPH radical scavenging activity and lipase and acetylcholinesterase inhibition assay of total methanol extract of plant material of the in vitro cultured plant. The following plant growth regulators were added to the control medium: 0.2 mg/L benzyl adenine (BA) + 0.02 mg/L 1-Naphthaleneacetic acid (NAA) (Sm); 0.2 mg/L BA + 0.5 mg/L NAA (Sr_1), 0.2 mg/L BA + 1.0 mg/L NAA (Sr_2), 0.5 mg/L BA + 0.5 mg/L NAA (Sr_3) and 0.5 mg/L BA + 1.0 mg/L NAA (Sr_4). As a general observation all treatments increased significantly the survival rate of explants, as well as polyphenolics productions as compared with the non-treated control. Strong relation between polyphenolic content and radical scavenging capacity were recorded and one probable lipase and and 2-4 components with acetylcholinesterase inhibition activity were identified. As a result of the work in vitro culture systems for optimal biomass production and secondary metabolites yield were selected. This work was financed by the PhytoBalk project (BSRP, grant No. IZEBZ0_142989). [1] Koleva P, Petrova N, Krumova S, Velikova V, Aneva I, Evstatieva L, Wolfram E, Danova K (2016) Planta Med 2016; 82(S 01): S1-S381
URI:	https://digitalcollection.zhaw.ch/handle/11475/1966
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	Life Sciences and Facility Management
Appears in collections:	Publikationen Life Sciences und Facility Management

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Danova, K., Wolfram, E., Pedrussio, S., Koleva, P., Aneva, I., & Evstatieva, L. (2017). Biotechnological development and biological activity of Balkan endemic Sideritis scardica Griesb. [Conference poster]. Planta Medica International Open, 4. https://doi.org/10.1055/s-0037-1608366

Danova, K. et al. (2017) ‘Biotechnological development and biological activity of Balkan endemic Sideritis scardica Griesb.’, in Planta Medica International Open. Thieme. Available at: https://doi.org/10.1055/s-0037-1608366.

K. Danova, E. Wolfram, S. Pedrussio, P. Koleva, I. Aneva, and L. Evstatieva, “Biotechnological development and biological activity of Balkan endemic Sideritis scardica Griesb.,” in Planta Medica International Open, 2017, vol. 4. doi: 10.1055/s-0037-1608366.

DANOVA, Kalina, Evelyn WOLFRAM, Simona PEDRUSSIO, Petya KOLEVA, Ina ANEVA und Luba EVSTATIEVA, 2017. Biotechnological development and biological activity of Balkan endemic Sideritis scardica Griesb. In: Planta Medica International Open. Conference poster. Thieme. 2017

Danova, Kalina, Evelyn Wolfram, Simona Pedrussio, Petya Koleva, Ina Aneva, and Luba Evstatieva. 2017. “Biotechnological Development and Biological Activity of Balkan Endemic Sideritis Scardica Griesb.” Conference poster. In Planta Medica International Open. Vol. 4. Thieme. https://doi.org/10.1055/s-0037-1608366.

Danova, Kalina, et al. “Biotechnological Development and Biological Activity of Balkan Endemic Sideritis Scardica Griesb.” Planta Medica International Open, vol. 4, Thieme, 2017, https://doi.org/10.1055/s-0037-1608366.