Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-1584
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dc.contributor.authorDemuth, Caspar-
dc.contributor.authorVaronier, Joel-
dc.contributor.authorJossen, Valentin-
dc.contributor.authorEibl-Schindler, Regine-
dc.contributor.authorEibl, Dieter-
dc.date.accessioned2018-01-29T15:32:42Z-
dc.date.available2018-01-29T15:32:42Z-
dc.date.issued2016-05-
dc.identifier.issn0175-7598de_CH
dc.identifier.issn1432-0614de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/2259-
dc.descriptionErworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)de_CH
dc.description.abstractpH value and the concentration of dissolved oxygen (DO) are key parameters to monitor and control cell growth in cultivation studies. Reliable, robust and accurate methods to measure these parameters in cultivation systems in real time guarantee high product yield and quality. This mini-review summarises the current state of the art of pH and DO sensors that are applied to bioprocesses from millilitre to benchtop scale by means of a short introduction on measuring principles and selected applications. Special emphasis is placed on single-use bioreactors, which have been increasingly employed in bioprocess development and production in recent years. Working principles, applications and the particular requirements of sensors in these cultivation systems are given. In such processes, optical sensors for pH and DO are often preferred to electrochemical probes, as they allow semi-invasive measurements and can be miniaturised to micrometre scale or lower. In addition, selected measuring principles of novel sensing technologies for pH and DO are discussed. These include solid-state sensors and miniaturised devices that are not yet commercially available, but show promising characteristics for possible use in bioprocesses in the near future.de_CH
dc.language.isoende_CH
dc.publisherSpringerde_CH
dc.relation.ispartofApplied Microbiology and Biotechnologyde_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectOptical sensorsde_CH
dc.subjectSingle-use cultivation systemsde_CH
dc.subjectBioprocess measurement and controlde_CH
dc.subjectSensors for pH and dissolved oxygende_CH
dc.subject.ddc660: Technische Chemiede_CH
dc.titleNovel probes for pH and dissolved oxygen measurements in cultivations from millilitre to benchtop scalede_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.publisher.placeBerlinde_CH
dc.identifier.doi10.21256/zhaw-1584-
dc.identifier.doi10.1007/s00253-016-7412-0de_CH
zhaw.funding.euNode_CH
zhaw.issue9de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end3863de_CH
zhaw.pages.start3853de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume100de_CH
zhaw.embargo.end2021-04-01de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
Appears in collections:Publikationen Life Sciences und Facility Management

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Demuth, C., Varonier, J., Jossen, V., Eibl-Schindler, R., & Eibl, D. (2016). Novel probes for pH and dissolved oxygen measurements in cultivations from millilitre to benchtop scale. Applied Microbiology and Biotechnology, 100(9), 3853–3863. https://doi.org/10.21256/zhaw-1584
Demuth, C. et al. (2016) ‘Novel probes for pH and dissolved oxygen measurements in cultivations from millilitre to benchtop scale’, Applied Microbiology and Biotechnology, 100(9), pp. 3853–3863. Available at: https://doi.org/10.21256/zhaw-1584.
C. Demuth, J. Varonier, V. Jossen, R. Eibl-Schindler, and D. Eibl, “Novel probes for pH and dissolved oxygen measurements in cultivations from millilitre to benchtop scale,” Applied Microbiology and Biotechnology, vol. 100, no. 9, pp. 3853–3863, May 2016, doi: 10.21256/zhaw-1584.
DEMUTH, Caspar, Joel VARONIER, Valentin JOSSEN, Regine EIBL-SCHINDLER und Dieter EIBL, 2016. Novel probes for pH and dissolved oxygen measurements in cultivations from millilitre to benchtop scale. Applied Microbiology and Biotechnology. Mai 2016. Bd. 100, Nr. 9, S. 3853–3863. DOI 10.21256/zhaw-1584
Demuth, Caspar, Joel Varonier, Valentin Jossen, Regine Eibl-Schindler, and Dieter Eibl. 2016. “Novel Probes for pH and Dissolved Oxygen Measurements in Cultivations from Millilitre to Benchtop Scale.” Applied Microbiology and Biotechnology 100 (9): 3853–63. https://doi.org/10.21256/zhaw-1584.
Demuth, Caspar, et al. “Novel Probes for pH and Dissolved Oxygen Measurements in Cultivations from Millilitre to Benchtop Scale.” Applied Microbiology and Biotechnology, vol. 100, no. 9, May 2016, pp. 3853–63, https://doi.org/10.21256/zhaw-1584.


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