Please use this identifier to cite or link to this item:
https://doi.org/10.21256/zhaw-25566
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Morel, Sandrine | - |
dc.contributor.author | Hostettler, Isabel C. | - |
dc.contributor.author | Spinner, Georg R. | - |
dc.contributor.author | Bourcier, Romain | - |
dc.contributor.author | Pera, Joanna | - |
dc.contributor.author | Meling, Torstein | - |
dc.contributor.author | Alg, Varinder | - |
dc.contributor.author | Houlden, Henry | - |
dc.contributor.author | Bakker, Mark | - |
dc.contributor.author | van’t Hof, Femke | - |
dc.contributor.author | Rinkel, Gabriel | - |
dc.contributor.author | Foroud, Tatiana | - |
dc.contributor.author | Lai, Dongbing | - |
dc.contributor.author | Moomaw, Charles | - |
dc.contributor.author | Worrall, Bradford | - |
dc.contributor.author | Caroff, Jildaz | - |
dc.contributor.author | Constant-dits-Beaufils, Pacôme | - |
dc.contributor.author | Karakachoff, Matilde | - |
dc.contributor.author | Rimbert, Antoine | - |
dc.contributor.author | Rouchaud, Aymeric | - |
dc.contributor.author | Gaal-Paavola, Emilia | - |
dc.contributor.author | Kaukovalta, Hanna | - |
dc.contributor.author | Kivisaari, Riku | - |
dc.contributor.author | Laakso, Aki | - |
dc.contributor.author | Jahromi, Behnam | - |
dc.contributor.author | Tulamo, Riikka | - |
dc.contributor.author | Friedrich, Christoph | - |
dc.contributor.author | Dauvillier, Jerome | - |
dc.contributor.author | Hirsch, Sven | - |
dc.contributor.author | Isidor, Nathalie | - |
dc.contributor.author | Kulcsàr, Zolt | - |
dc.contributor.author | Lövblad, Karl | - |
dc.contributor.author | Martin, Olivier | - |
dc.contributor.author | Machi, Paolo | - |
dc.contributor.author | Mendes Pereira, Vitor | - |
dc.contributor.author | Rüfenacht, Daniel | - |
dc.contributor.author | Schaller, Karl | - |
dc.contributor.author | Schilling, Sabine | - |
dc.contributor.author | Slowik, Agnieszka | - |
dc.contributor.author | Jaaskelainen, Juha | - |
dc.contributor.author | von und zu Fraunberg, Mikael | - |
dc.contributor.author | Jiménez-Conde, Jordi | - |
dc.contributor.author | Cuadrado-Godia, Elisa | - |
dc.contributor.author | Soriano-Tárraga, Carolina | - |
dc.contributor.author | Millwood, Iona | - |
dc.contributor.author | Walters, Robin | - |
dc.contributor.author | The @neurIST project | - |
dc.contributor.author | The ICAN Study Group | - |
dc.contributor.author | Genetics and Observational Subarachnoid Haemorrhage (GOSH) Study Investigators | - |
dc.contributor.author | International Stroke Genetics Consortium (ISGC) | - |
dc.contributor.author | Kim, Helen | - |
dc.contributor.author | Redon, Richard | - |
dc.contributor.author | Ko, Nerissa | - |
dc.contributor.author | Rouleau, Guy | - |
dc.contributor.author | Lindgren, Antti | - |
dc.contributor.author | Niemelä, Mika | - |
dc.contributor.author | Desal, Hubert | - |
dc.contributor.author | Woo, Daniel | - |
dc.contributor.author | Broderick, Joseph | - |
dc.contributor.author | Werring, David | - |
dc.contributor.author | Ruigrok, Ynte | - |
dc.contributor.author | Bijlenga, Philippe | - |
dc.date.accessioned | 2022-09-08T08:47:24Z | - |
dc.date.available | 2022-09-08T08:47:24Z | - |
dc.date.issued | 2022 | - |
dc.identifier.issn | 2075-4426 | de_CH |
dc.identifier.uri | https://digitalcollection.zhaw.ch/handle/11475/25566 | - |
dc.description.abstract | Intracranial aneurysms (IAs) are usually asymptomatic with a low risk of rupture, but consequences of aneurysmal subarachnoid hemorrhage (aSAH) are severe. Identifying IAs at risk of rupture has important clinical and socio-economic consequences. The goal of this study was to assess the effect of patient and IA characteristics on the likelihood of IA being diagnosed incidentally versus ruptured. Patients were recruited at 21 international centers. Seven phenotypic patient characteristics and three IA characteristics were recorded. The analyzed cohort included 7992 patients. Multivariate analysis demonstrated that: (1) IA location is the strongest factor associated with IA rupture status at diagnosis; (2) Risk factor awareness (hypertension, smoking) increases the likelihood of being diagnosed with unruptured IA; (3) Patients with ruptured IAs in high-risk locations tend to be older, and their IAs are smaller; (4) Smokers with ruptured IAs tend to be younger, and their IAs are larger; (5) Female patients with ruptured IAs tend to be older, and their IAs are smaller; (6) IA size and age at rupture correlate. The assessment of associations regarding patient and IA characteristics with IA rupture allows us to refine IA disease models and provide data to develop risk instruments for clinicians to support personalized decision-making. | de_CH |
dc.language.iso | en | de_CH |
dc.publisher | MDPI | de_CH |
dc.relation.ispartof | Journal of Personalized Medicine | de_CH |
dc.rights | http://creativecommons.org/licenses/by/4.0/ | de_CH |
dc.subject | Intracranial aneurysm | de_CH |
dc.subject | Subarachnoid hemorrhage | de_CH |
dc.subject | Risk factor | de_CH |
dc.subject | Location | de_CH |
dc.subject | Smoking | de_CH |
dc.subject | Hypertension | de_CH |
dc.subject.ddc | 006: Spezielle Computerverfahren | de_CH |
dc.subject.ddc | 616: Innere Medizin und Krankheiten | de_CH |
dc.title | Intracranial aneurysm classifier using phenotypic factors : an international pooled analysis | de_CH |
dc.type | Beitrag in wissenschaftlicher Zeitschrift | de_CH |
dcterms.type | Text | de_CH |
zhaw.departement | Life Sciences und Facility Management | de_CH |
zhaw.organisationalunit | Institut für Computational Life Sciences (ICLS) | de_CH |
dc.identifier.doi | 10.3390/jpm12091410 | de_CH |
dc.identifier.doi | 10.21256/zhaw-25566 | - |
zhaw.funding.eu | No | de_CH |
zhaw.issue | 9 | de_CH |
zhaw.originated.zhaw | Yes | de_CH |
zhaw.pages.start | 1410 | de_CH |
zhaw.publication.status | publishedVersion | de_CH |
zhaw.volume | 12 | de_CH |
zhaw.publication.review | Peer review (Publikation) | de_CH |
zhaw.webfeed | Biomedical Simulation | de_CH |
zhaw.funding.zhaw | AneuX | de_CH |
zhaw.author.additional | No | de_CH |
zhaw.display.portrait | Yes | de_CH |
Appears in collections: | Publikationen Life Sciences und Facility Management |
Files in This Item:
File | Description | Size | Format | |
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2022_Morel-etal_Inracranial-aneurysm-classifier.pdf | 2.51 MB | Adobe PDF | ![]() View/Open |
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