| Publication type: | Article in scientific journal |
| Type of review: | Peer review (publication) |
| Title: | Pseudouridimycin : the first nucleoside analogue that selectively inhibits bacterial RNA polymerase |
| Authors: | Chellat, Mathieu F. Riedl, Rainer |
| DOI: | 10.1002/anie.201708133 |
| Published in: | Angewandte Chemie: International Edition |
| Volume(Issue): | 56 |
| Issue: | 43 |
| Page(s): | 13184 |
| Pages to: | 13186 |
| Issue Date: | 2017 |
| Publisher / Ed. Institution: | Wiley |
| ISSN: | 1433-7851 0570-0833 |
| Language: | English |
| Subjects: | RNA polymerase; Antibiotics; Medicinal chemistry; Natural products; Nucleoside analogues |
| Subject (DDC): | 615: Pharmacology and therapeutics |
| Abstract: | Seek, and ye shall find: After years of focusing research on synthetic antibiotics out of fear that all the useful natural ones had already been found, a novel antibacterial compound has been discovered through conventional microbial extract screening. The broad-spectrum nucleoside-analogue inhibitor pseudouridimycin is selective for bacterial RNA polymerase and elicits very low resistance rates. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/2881 |
| Fulltext version: | Published version |
| License (according to publishing contract): | Licence according to publishing contract |
| Departement: | Life Sciences and Facility Management |
| Appears in collections: | Publikationen Life Sciences und Facility Management |
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Chellat, M. F., & Riedl, R. (2017). Pseudouridimycin : the first nucleoside analogue that selectively inhibits bacterial RNA polymerase. Angewandte Chemie: International Edition, 56(43), 13184–13186. https://doi.org/10.1002/anie.201708133
Chellat, M.F. and Riedl, R. (2017) ‘Pseudouridimycin : the first nucleoside analogue that selectively inhibits bacterial RNA polymerase’, Angewandte Chemie: International Edition, 56(43), pp. 13184–13186. Available at: https://doi.org/10.1002/anie.201708133.
M. F. Chellat and R. Riedl, “Pseudouridimycin : the first nucleoside analogue that selectively inhibits bacterial RNA polymerase,” Angewandte Chemie: International Edition, vol. 56, no. 43, pp. 13184–13186, 2017, doi: 10.1002/anie.201708133.
CHELLAT, Mathieu F. und Rainer RIEDL, 2017. Pseudouridimycin : the first nucleoside analogue that selectively inhibits bacterial RNA polymerase. Angewandte Chemie: International Edition. 2017. Bd. 56, Nr. 43, S. 13184–13186. DOI 10.1002/anie.201708133
Chellat, Mathieu F., and Rainer Riedl. 2017. “Pseudouridimycin : The First Nucleoside Analogue That Selectively Inhibits Bacterial RNA Polymerase.” Angewandte Chemie: International Edition 56 (43): 13184–86. https://doi.org/10.1002/anie.201708133.
Chellat, Mathieu F., and Rainer Riedl. “Pseudouridimycin : The First Nucleoside Analogue That Selectively Inhibits Bacterial RNA Polymerase.” Angewandte Chemie: International Edition, vol. 56, no. 43, 2017, pp. 13184–86, https://doi.org/10.1002/anie.201708133.
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