Publication type: Article in scientific journal
Type of review: Peer review (publication)
Title: Novel hyperthermia applicator system allows adaptive treatment planning : preliminary clinical results in tumour-bearing animals
Authors: Dressel, S.
Gosselin, M.-C.
Capstick, M. H.
Carrasco, E.
Weyland, Mathias
Scheidegger, Stephan
Neufeld, E.
Kuster, N.
Bodis, S.
Rohrer Bley, C.
DOI: 10.1111/vco.12340
Published in: Veterinary and Comparative Oncology
Volume(Issue): 16
Issue: 2
Page(s): 202
Pages to: 213
Issue Date: 2017
Publisher / Ed. Institution: Wiley
ISSN: 1476-5810
1476-5829
Language: English
Subjects: adaptive treatment planning; Cat; Dog; Hyperthermia; Radiation; Tumour
Subject (DDC): 615: Pharmacology and therapeutics
630: Agriculture
Abstract: Hyperthermia (HT) as an adjuvant to radiation therapy (RT) is a multimodality treatment method to enhance therapeutic efficacy in different tumours. High demands are placed on the hardware and treatment planning software to guarantee adequately planned and applied HT treatments. The aim of this prospective study was to determine the effectiveness and safety of the novel HT system in tumour-bearing dogs and cats in terms of local response and toxicity as well as to compare planned with actual achieved data during heating. A novel applicator with a flexible number of elements and integrated closed-loop temperature feedback control system, and a tool for patient-specific treatment planning were used in a combined thermoradiotherapy protocol. Good agreement between predictions from planning and clinical outcome was found in 7 of 8 cases. Effective HT treatments were planned and verified with the novel system and provided improved quality of life in all but 1 patient. This individualized treatment planning and controlled heat exposure allows adaptive, flexible and safe HT treatments in palliatively treated animal patients.
URI: https://digitalcollection.zhaw.ch/handle/11475/4714
Fulltext version: Published version
License (according to publishing contract): Licence according to publishing contract
Departement: School of Engineering
Appears in collections:Publikationen School of Engineering

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Dressel, S., Gosselin, M.-C., Capstick, M. H., Carrasco, E., Weyland, M., Scheidegger, S., Neufeld, E., Kuster, N., Bodis, S., & Rohrer Bley, C. (2017). Novel hyperthermia applicator system allows adaptive treatment planning : preliminary clinical results in tumour-bearing animals. Veterinary and Comparative Oncology, 16(2), 202–213. https://doi.org/10.1111/vco.12340
Dressel, S. et al. (2017) ‘Novel hyperthermia applicator system allows adaptive treatment planning : preliminary clinical results in tumour-bearing animals’, Veterinary and Comparative Oncology, 16(2), pp. 202–213. Available at: https://doi.org/10.1111/vco.12340.
S. Dressel et al., “Novel hyperthermia applicator system allows adaptive treatment planning : preliminary clinical results in tumour-bearing animals,” Veterinary and Comparative Oncology, vol. 16, no. 2, pp. 202–213, 2017, doi: 10.1111/vco.12340.
DRESSEL, S., M.-C. GOSSELIN, M. H. CAPSTICK, E. CARRASCO, Mathias WEYLAND, Stephan SCHEIDEGGER, E. NEUFELD, N. KUSTER, S. BODIS und C. ROHRER BLEY, 2017. Novel hyperthermia applicator system allows adaptive treatment planning : preliminary clinical results in tumour-bearing animals. Veterinary and Comparative Oncology. 2017. Bd. 16, Nr. 2, S. 202–213. DOI 10.1111/vco.12340
Dressel, S., M.-C. Gosselin, M. H. Capstick, E. Carrasco, Mathias Weyland, Stephan Scheidegger, E. Neufeld, N. Kuster, S. Bodis, and C. Rohrer Bley. 2017. “Novel Hyperthermia Applicator System Allows Adaptive Treatment Planning : Preliminary Clinical Results in Tumour-Bearing Animals.” Veterinary and Comparative Oncology 16 (2): 202–13. https://doi.org/10.1111/vco.12340.
Dressel, S., et al. “Novel Hyperthermia Applicator System Allows Adaptive Treatment Planning : Preliminary Clinical Results in Tumour-Bearing Animals.” Veterinary and Comparative Oncology, vol. 16, no. 2, 2017, pp. 202–13, https://doi.org/10.1111/vco.12340.


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