Publication type: | Article in scientific journal |
Type of review: | Peer review (publication) |
Title: | Current and upcoming therapies to modulate skin scarring and fibrosis |
Authors: | Coentro, João Q. Pugliese, Eugenia Hanley, Geoffrey Raghunath, Michael Zeugolis, Dimitrios I. |
DOI: | 10.1016/j.addr.2018.08.009 |
Published in: | Advanced Drug Delivery Reviews |
Issue Date: | 2018 |
Publisher / Ed. Institution: | Elsevier |
ISSN: | 0169-409X 1872-8294 |
Language: | English |
Subject (DDC): | 617: Surgery |
Abstract: | Skin is the largest organ of the human body. Being the interface between the body and the outer environment, makes it susceptible to physical injury. To maintain life, nature has endowed skin with a fast healing response that invariably ends in the formation of scar at the wounded dermal area. In many cases, skin remodelling may be impaired, leading to local hypertrophic scars or keloids. One should also consider that the scarring process is part of the wound healing response, which always starts with inflammation. Thus, scarring can also be induced in the dermis, in the absence of an actual wound, during chronic inflammatory processes. Considering the significant portion of the population that is subject to abnormal scarring, this review critically discusses the state-of-the-art and upcoming therapies in skin scarring and fibrosis. |
URI: | https://digitalcollection.zhaw.ch/handle/11475/12107 |
Fulltext version: | Published version |
License (according to publishing contract): | Licence according to publishing contract |
Departement: | Life Sciences and Facility Management |
Organisational Unit: | Institute of Chemistry and Biotechnology (ICBT) |
Appears in collections: | Publikationen Life Sciences und Facility Management |
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Coentro, J. Q., Pugliese, E., Hanley, G., Raghunath, M., & Zeugolis, D. I. (2018). Current and upcoming therapies to modulate skin scarring and fibrosis. Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2018.08.009
Coentro, J.Q. et al. (2018) ‘Current and upcoming therapies to modulate skin scarring and fibrosis’, Advanced Drug Delivery Reviews [Preprint]. Available at: https://doi.org/10.1016/j.addr.2018.08.009.
J. Q. Coentro, E. Pugliese, G. Hanley, M. Raghunath, and D. I. Zeugolis, “Current and upcoming therapies to modulate skin scarring and fibrosis,” Advanced Drug Delivery Reviews, 2018, doi: 10.1016/j.addr.2018.08.009.
COENTRO, João Q., Eugenia PUGLIESE, Geoffrey HANLEY, Michael RAGHUNATH und Dimitrios I. ZEUGOLIS, 2018. Current and upcoming therapies to modulate skin scarring and fibrosis. Advanced Drug Delivery Reviews. 2018. DOI 10.1016/j.addr.2018.08.009
Coentro, João Q., Eugenia Pugliese, Geoffrey Hanley, Michael Raghunath, and Dimitrios I. Zeugolis. 2018. “Current and Upcoming Therapies to Modulate Skin Scarring and Fibrosis.” Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2018.08.009.
Coentro, João Q., et al. “Current and Upcoming Therapies to Modulate Skin Scarring and Fibrosis.” Advanced Drug Delivery Reviews, 2018, https://doi.org/10.1016/j.addr.2018.08.009.
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