Publication type: | Article in scientific journal |
Type of review: | Peer review (publication) |
Title: | Mortality of 403 patients with mood disorders 48 to 52 years after their psychiatric hospitalisation |
Authors: | Angst, Jules Hengartner, Michael Pascal Gamma, Alex von Zerssen, Detlev Angst, Felix |
DOI: | 10.1007/s00406-012-0380-1 |
Published in: | European Archives of Psychiatry and Clinical Neuroscience |
Volume(Issue): | 263 |
Issue: | 5 |
Page(s): | 425 |
Pages to: | 434 |
Issue Date: | 2012 |
Publisher / Ed. Institution: | Springer |
ISSN: | 0940-1334 1433-8491 |
Language: | English |
Subjects: | Female; Humans; Longitudinal Studies; Male; Middle Aged; Mood Disorders; Psychiatric Status Rating Scales; Regression Analysis; Survival Analysis; Hospitals, Psychiatric |
Subject (DDC): | 616.8: Neurology, diseases of nervous system |
Abstract: | The purpose is to analyse differences in mortality among patients with major depressive disorders (MDD), bipolar-II (BP-II), bipolar-I (BP-I) disorders and mania with or without minor depressive disorders and to identify risk factors of mortality. The sample represents all admissions for depression or mania over 5 years (1959-1963) to the Psychiatric Hospital of Zurich University, serving a large area. 403 patients were included and followed up every 5 years until 1985; thereafter, mortality data were collected repeatedly until 2009 when 352 (87%) patients had died. Standardised mortality ratios (SMRs) were computed and survival analyses applied. With the exception of BP-II disorder, the three other diagnostic groups showed elevated SMRs. The group with mania had the highest SMR for cardiovascular deaths and the group with MDD the highest for deaths by suicide. Mortality was also high among patients with late-onset MDD. Across the diagnostic spectrum, we found differences in risk factors for mortality, such as a family history of suicides and personality type: more anxious patients with MDD lived longer, and among patients with BP disorders, more tense (aggressive) types had shorter lives. Long-term medication had a protective effect against mortality in patients with MDD during years 1-9 and in patients with BP disorders during years 1-19 after admission. We found marked differences in causes of death and risk factors between subgroups of mood disorders. For the purpose of further research, it would be recommendable to distinguish pure mania from bipolar disorders. |
URI: | https://digitalcollection.zhaw.ch/handle/11475/15118 |
Fulltext version: | Published version |
License (according to publishing contract): | Licence according to publishing contract |
Departement: | Applied Psychology |
Organisational Unit: | Psychological Institute (PI) |
Appears in collections: | Publikationen Angewandte Psychologie |
Files in This Item:
There are no files associated with this item.
Show full item record
Angst, J., Hengartner, M. P., Gamma, A., von Zerssen, D., & Angst, F. (2012). Mortality of 403 patients with mood disorders 48 to 52 years after their psychiatric hospitalisation. European Archives of Psychiatry and Clinical Neuroscience, 263(5), 425–434. https://doi.org/10.1007/s00406-012-0380-1
Angst, J. et al. (2012) ‘Mortality of 403 patients with mood disorders 48 to 52 years after their psychiatric hospitalisation’, European Archives of Psychiatry and Clinical Neuroscience, 263(5), pp. 425–434. Available at: https://doi.org/10.1007/s00406-012-0380-1.
J. Angst, M. P. Hengartner, A. Gamma, D. von Zerssen, and F. Angst, “Mortality of 403 patients with mood disorders 48 to 52 years after their psychiatric hospitalisation,” European Archives of Psychiatry and Clinical Neuroscience, vol. 263, no. 5, pp. 425–434, 2012, doi: 10.1007/s00406-012-0380-1.
ANGST, Jules, Michael Pascal HENGARTNER, Alex GAMMA, Detlev VON ZERSSEN und Felix ANGST, 2012. Mortality of 403 patients with mood disorders 48 to 52 years after their psychiatric hospitalisation. European Archives of Psychiatry and Clinical Neuroscience. 2012. Bd. 263, Nr. 5, S. 425–434. DOI 10.1007/s00406-012-0380-1
Angst, Jules, Michael Pascal Hengartner, Alex Gamma, Detlev von Zerssen, and Felix Angst. 2012. “Mortality of 403 Patients with Mood Disorders 48 to 52 Years after Their Psychiatric Hospitalisation.” European Archives of Psychiatry and Clinical Neuroscience 263 (5): 425–34. https://doi.org/10.1007/s00406-012-0380-1.
Angst, Jules, et al. “Mortality of 403 Patients with Mood Disorders 48 to 52 Years after Their Psychiatric Hospitalisation.” European Archives of Psychiatry and Clinical Neuroscience, vol. 263, no. 5, 2012, pp. 425–34, https://doi.org/10.1007/s00406-012-0380-1.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.