Please use this identifier to cite or link to this item:
https://doi.org/10.21256/zhaw-2796Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Peters, Christin | - |
| dc.contributor.author | Buller, Rebecca | - |
| dc.date.accessioned | 2019-03-28T13:20:16Z | - |
| dc.date.available | 2019-03-28T13:20:16Z | - |
| dc.date.issued | 2019 | - |
| dc.identifier.issn | 2073-4344 | de_CH |
| dc.identifier.uri | https://digitalcollection.zhaw.ch/handle/11475/16369 | - |
| dc.description.abstract | C-H functionalization is a chemically challenging but highly desirable transformation. 2-oxoglutarate-dependent oxygenases (2OGXs) are remarkably versatile biocatalysts for the activation of C-H bonds. In nature, they have been shown to accept both small and large molecules carrying out a plethora of reactions, including hydroxylations, demethylations, ring formations, rearrangements, desaturations, and halogenations, making them promising candidates for industrial manufacture. In this review, we describe the current status of 2OGX use in biocatalytic applications concentrating on 2OGX-catalyzed oxyfunctionalization of amino acids and synthesis of antibiotics. Looking forward, continued bioinformatic sourcing will help identify additional, practical useful members of this intriguing enzyme family, while enzyme engineering will pave the way to enhance 2OGX reactivity for non-native substrates. | de_CH |
| dc.language.iso | de | de_CH |
| dc.publisher | MDPI | de_CH |
| dc.relation.ispartof | Catalysts | de_CH |
| dc.rights | http://creativecommons.org/licenses/by/4.0/ | de_CH |
| dc.subject.ddc | 660.6: Biotechnologie | de_CH |
| dc.title | Industrial application of 2-oxoglutarate-dependent oxygenases | de_CH |
| dc.type | Beitrag in wissenschaftlicher Zeitschrift | de_CH |
| dcterms.type | Text | de_CH |
| zhaw.departement | Life Sciences und Facility Management | de_CH |
| zhaw.organisationalunit | Institut für Chemie und Biotechnologie (ICBT) | de_CH |
| dc.identifier.doi | 10.21256/zhaw-2796 | - |
| dc.identifier.doi | 10.3390/catal9030221 | de_CH |
| zhaw.funding.eu | No | de_CH |
| zhaw.issue | 3 | de_CH |
| zhaw.originated.zhaw | Yes | de_CH |
| zhaw.pages.end | 240 | de_CH |
| zhaw.pages.start | 221 | de_CH |
| zhaw.publication.status | publishedVersion | de_CH |
| zhaw.volume | 9 | de_CH |
| zhaw.publication.review | Peer review (Publikation) | de_CH |
| zhaw.webfeed | Biokatalyse | de_CH |
| Appears in collections: | Publikationen Life Sciences und Facility Management | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2019_Peters_Bullers_Industrial application of 2-oxoglutarate-dependent oxygenases_Catalysts.pdf | 1.6 MB | Adobe PDF |  View/Open |
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Peters, C., & Buller, R. (2019). Industrial application of 2-oxoglutarate-dependent oxygenases. Catalysts, 9(3), 221–240. https://doi.org/10.21256/zhaw-2796
Peters, C. and Buller, R. (2019) ‘Industrial application of 2-oxoglutarate-dependent oxygenases’, Catalysts, 9(3), pp. 221–240. Available at: https://doi.org/10.21256/zhaw-2796.
C. Peters and R. Buller, “Industrial application of 2-oxoglutarate-dependent oxygenases,” Catalysts, vol. 9, no. 3, pp. 221–240, 2019, doi: 10.21256/zhaw-2796.
PETERS, Christin und Rebecca BULLER, 2019. Industrial application of 2-oxoglutarate-dependent oxygenases. Catalysts. 2019. Bd. 9, Nr. 3, S. 221–240. DOI 10.21256/zhaw-2796
Peters, Christin, and Rebecca Buller. 2019. “Industrial application of 2-oxoglutarate-dependent oxygenases.” Catalysts 9 (3): 221–40. https://doi.org/10.21256/zhaw-2796.
Peters, Christin, and Rebecca Buller. “Industrial application of 2-oxoglutarate-dependent oxygenases.” Catalysts, vol. 9, no. 3, 2019, pp. 221–40, https://doi.org/10.21256/zhaw-2796.
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