Diversity and function of phage encoded depolymerases

Knecht, Leandra E.; Veljkovic, Marjan; Fieseler, Lars

doi:10.3389/fmicb.2019.02949

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-19174

Publication type:	Article in scientific journal
Type of review:	Open peer review
Title:	Diversity and function of phage encoded depolymerases
Authors:	Knecht, Leandra E. Veljkovic, Marjan Fieseler, Lars
et. al:	No
DOI:	10.3389/fmicb.2019.02949 10.21256/zhaw-19174
Published in:	Frontiers in Microbiology
Volume(Issue):	10
Issue:	2949
Issue Date:	Jan-2020
Publisher / Ed. Institution:	Frontiers Research Foundation
ISSN:	1664-302X
Language:	English
Subjects:	Phage; Tail spike protein; Depolymerase
Subject (DDC):	570: Biology 660.6: Biotechnology
Abstract:	Bacteriophages of the Podoviridae family often exhibit so-called depolymerases as structural components of the virion. These enzymes appear as tail spike proteins (TSPs). After specific binding to capsular polysaccharides (CPS), exopolysaccharides (EPS) or lipopolysaccharide (LPS) of the host bacteria, polysaccharide-repeating units are specifically cleaved. Finally, the phage reaches the last barrier, the cell wall, injects its DNA, and infects the cell. Recently, similar enzymes from bacteriophages of the Ackermannviridae, Myoviridae, and Siphoviridae families were also described. In this mini-review the diversity and function of phage encoded CPS-, EPS-, and LPSdegrading depolymerases is summarized. The function of the enzymes is described in terms of substrate specificity and applications in biotechnology.
URI:	https://digitalcollection.zhaw.ch/handle/11475/19174
Fulltext version:	Published version
License (according to publishing contract):	CC BY 4.0: Attribution 4.0 International
Departement:	Life Sciences and Facility Management
Organisational Unit:	Institute of Food and Beverage Innovation (ILGI)
Published as part of the ZHAW project:	Nachweis von Pseudomonas aeruginosa mittels Durchflusszytometrie
Appears in collections:	Publikationen Life Sciences und Facility Management

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Knecht, L. E., Veljkovic, M., & Fieseler, L. (2020). Diversity and function of phage encoded depolymerases. Frontiers in Microbiology, 10(2949). https://doi.org/10.3389/fmicb.2019.02949

Knecht, L.E., Veljkovic, M. and Fieseler, L. (2020) ‘Diversity and function of phage encoded depolymerases’, Frontiers in Microbiology, 10(2949). Available at: https://doi.org/10.3389/fmicb.2019.02949.

L. E. Knecht, M. Veljkovic, and L. Fieseler, “Diversity and function of phage encoded depolymerases,” Frontiers in Microbiology, vol. 10, no. 2949, Jan. 2020, doi: 10.3389/fmicb.2019.02949.

KNECHT, Leandra E., Marjan VELJKOVIC und Lars FIESELER, 2020. Diversity and function of phage encoded depolymerases. Frontiers in Microbiology. Januar 2020. Bd. 10, Nr. 2949. DOI 10.3389/fmicb.2019.02949

Knecht, Leandra E., Marjan Veljkovic, and Lars Fieseler. 2020. “Diversity and Function of Phage Encoded Depolymerases.” Frontiers in Microbiology 10 (2949). https://doi.org/10.3389/fmicb.2019.02949.

Knecht, Leandra E., et al. “Diversity and Function of Phage Encoded Depolymerases.” Frontiers in Microbiology, vol. 10, no. 2949, Jan. 2020, https://doi.org/10.3389/fmicb.2019.02949.