Publication type: | Article in scientific journal |
Type of review: | Peer review (publication) |
Title: | Development of the travelling wave bioreactor. Part II : engineering characteristics and cultivation results |
Authors: | Kaiser, Stephan Perepelitsa, Nadja Kraume, Matthias Eibl, Dieter |
DOI: | 10.1002/cite.201500091 |
Published in: | Chemie Ingenieur Technik |
Volume(Issue): | 88 |
Issue: | 1-2 |
Page(s): | 86 |
Pages to: | 92 |
Issue Date: | Feb-2016 |
Publisher / Ed. Institution: | Wiley |
Publisher / Ed. Institution: | Weinheim |
ISSN: | 0009-286X 1522-2640 |
Language: | English |
Subject (DDC): | 660: Chemical engineering |
Abstract: | The innovative travelling wave bioreactor (TWB), an orbitally shaken system, developed specifically for cell culture applications, is investigated. In this study, engineering parameters covering power input, mixing time and oxygen mass transfer obtained in two TWB prototypes are presented for the first time. Based on the results, cultivation parameters for CHO suspension cell cultivations were defined. Cell growth and substrate consumption were comparable with a wave-mixed reference bioreactor, which demonstrates the bioreactor's applicability for cultivations of mammalian cell cultures for the first time. |
URI: | https://digitalcollection.zhaw.ch/handle/11475/2229 |
Fulltext version: | Published version |
License (according to publishing contract): | Licence according to publishing contract |
Departement: | Life Sciences and Facility Management |
Appears in collections: | Publikationen Life Sciences und Facility Management |
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Kaiser, S., Perepelitsa, N., Kraume, M., & Eibl, D. (2016). Development of the travelling wave bioreactor. Part II : engineering characteristics and cultivation results. Chemie Ingenieur Technik, 88(1-2), 86–92. https://doi.org/10.1002/cite.201500091
Kaiser, S. et al. (2016) ‘Development of the travelling wave bioreactor. Part II : engineering characteristics and cultivation results’, Chemie Ingenieur Technik, 88(1-2), pp. 86–92. Available at: https://doi.org/10.1002/cite.201500091.
S. Kaiser, N. Perepelitsa, M. Kraume, and D. Eibl, “Development of the travelling wave bioreactor. Part II : engineering characteristics and cultivation results,” Chemie Ingenieur Technik, vol. 88, no. 1-2, pp. 86–92, Feb. 2016, doi: 10.1002/cite.201500091.
KAISER, Stephan, Nadja PEREPELITSA, Matthias KRAUME und Dieter EIBL, 2016. Development of the travelling wave bioreactor. Part II : engineering characteristics and cultivation results. Chemie Ingenieur Technik. Februar 2016. Bd. 88, Nr. 1-2, S. 86–92. DOI 10.1002/cite.201500091
Kaiser, Stephan, Nadja Perepelitsa, Matthias Kraume, and Dieter Eibl. 2016. “Development of the Travelling Wave Bioreactor. Part II : Engineering Characteristics and Cultivation Results.” Chemie Ingenieur Technik 88 (1-2): 86–92. https://doi.org/10.1002/cite.201500091.
Kaiser, Stephan, et al. “Development of the Travelling Wave Bioreactor. Part II : Engineering Characteristics and Cultivation Results.” Chemie Ingenieur Technik, vol. 88, no. 1-2, Feb. 2016, pp. 86–92, https://doi.org/10.1002/cite.201500091.
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