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dc.contributor.authorLöffelholz, Christian-
dc.contributor.authorHusemann, Ute-
dc.contributor.authorGreller, Gerhard-
dc.contributor.authorMeusel, Wolfram-
dc.contributor.authorKauling, Jörg-
dc.contributor.authorAy, Peter-
dc.contributor.authorKraume, Matthias-
dc.contributor.authorEibl-Schindler, Regine-
dc.contributor.authorEibl, Dieter-
dc.date.accessioned2018-01-29T14:58:25Z-
dc.date.available2018-01-29T14:58:25Z-
dc.date.issued2013-02-
dc.identifier.issn0009-286Xde_CH
dc.identifier.issn1522-2640de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/2245-
dc.description.abstractDuring the past five years, the number of single-use bioreactors used in biopharmaceutical research and production has increased tremendously. This increase has been particularly associated with mammalian cell culture processes from small- to medium-scale volumes. Even though nowadays customers can choose from a multitude of 2nd and 3rd generation single-use bioreactors, ranging from mL- up to m3-scale, there is a lack of knowledge of their engineering parameters. Different approaches have been applied to characterization investigations, resulting in an inability to compare different single-use bioreactors with each other and their reusable counterparts, creating an obstacle to a systematic approach to scaling-up the process. This article describes parametric, experimental and computer-based numeric methods for biochemical engineering characterization of single-use bioreactors, which have already been used successfully for the characterization of their reusable counterparts. For the first time, these methods have been evaluated in terms of their practical application.de_CH
dc.language.isoende_CH
dc.publisherWileyde_CH
dc.relation.ispartofChemie Ingenieur Technikde_CH
dc.rightsLicence according to publishing contractde_CH
dc.subject.ddc660: Technische Chemiede_CH
dc.titleBioengineering parameters for single-use bioreactors : overview and evaluation of suitable methodsde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
zhaw.publisher.placeWeinheimde_CH
dc.identifier.doi10.1002/cite.201200125de_CH
zhaw.funding.euNode_CH
zhaw.issue1-2de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end56de_CH
zhaw.pages.start40de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume85de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
Appears in collections:Publikationen Life Sciences und Facility Management

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Löffelholz, C., Husemann, U., Greller, G., Meusel, W., Kauling, J., Ay, P., Kraume, M., Eibl-Schindler, R., & Eibl, D. (2013). Bioengineering parameters for single-use bioreactors : overview and evaluation of suitable methods. Chemie Ingenieur Technik, 85(1-2), 40–56. https://doi.org/10.1002/cite.201200125
Löffelholz, C. et al. (2013) ‘Bioengineering parameters for single-use bioreactors : overview and evaluation of suitable methods’, Chemie Ingenieur Technik, 85(1-2), pp. 40–56. Available at: https://doi.org/10.1002/cite.201200125.
C. Löffelholz et al., “Bioengineering parameters for single-use bioreactors : overview and evaluation of suitable methods,” Chemie Ingenieur Technik, vol. 85, no. 1-2, pp. 40–56, Feb. 2013, doi: 10.1002/cite.201200125.
LÖFFELHOLZ, Christian, Ute HUSEMANN, Gerhard GRELLER, Wolfram MEUSEL, Jörg KAULING, Peter AY, Matthias KRAUME, Regine EIBL-SCHINDLER und Dieter EIBL, 2013. Bioengineering parameters for single-use bioreactors : overview and evaluation of suitable methods. Chemie Ingenieur Technik. Februar 2013. Bd. 85, Nr. 1-2, S. 40–56. DOI 10.1002/cite.201200125
Löffelholz, Christian, Ute Husemann, Gerhard Greller, Wolfram Meusel, Jörg Kauling, Peter Ay, Matthias Kraume, Regine Eibl-Schindler, and Dieter Eibl. 2013. “Bioengineering Parameters for Single-Use Bioreactors : Overview and Evaluation of Suitable Methods.” Chemie Ingenieur Technik 85 (1-2): 40–56. https://doi.org/10.1002/cite.201200125.
Löffelholz, Christian, et al. “Bioengineering Parameters for Single-Use Bioreactors : Overview and Evaluation of Suitable Methods.” Chemie Ingenieur Technik, vol. 85, no. 1-2, Feb. 2013, pp. 40–56, https://doi.org/10.1002/cite.201200125.


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