Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-24231
Publication type: Article in scientific journal
Type of review: No review
Title: Cross-industrial applications of organotypic models
Authors: Kopanska, Katarzyna S
Rimann, Markus
et. al: No
DOI: 10.14573/altex.2112202
10.21256/zhaw-24231
Published in: ALTEX - Alternatives to Animal Experimentation
Volume(Issue): 39
Issue: 1
Pages: 155
Pages to: 158
Issue Date: 2022
Publisher / Ed. Institution: Springer
ISSN: 1868-596X
1868-8551
Language: English
Subjects: Microphysiological system; Cross-sectoral collaboration; 3D cell culture; Drug development; Human-relevant test system; Alternative method; Lab-On-A-Chip device; 3Rs principle; Biofabrication
Subject (DDC): 610.28: Biomedicine, biomedical engineering
Abstract: Recent advances in microphysiological systems (MPS) promise a global paradigm shift in drug development, diagnostics, disease prevention, and therapy. The expectation is that these systems will model healthy and various diseased stages and disease progression to predict toxicity, immunogenicity, ADME profiles, and treatment efficacies. MPS will provide unprecedented human-like physiological properties of in vitro models, enabling their routine application in the pharma industry and thus reducing drug development costs by lowering the attrition rate of compounds. We showcased MPS application diversity across different industries during the TEDD Annual Meeting on 14th October 2021 in W├Ądenswil, Switzerland. The goal was to promote cross-sectoral collaboration of academia and industry to further pave the way for developing next-generation MPS based on 3D cell culture, organoid, and organ-on-chip technology and their widespread exploitation. To enable visionary projects and radical innovations, we covered multidisciplinary fields and connected different industry sectors, like pharma, medtech, biotech, cosmetics, diagnostics, fragrances, and food, with each other.
URI: https://digitalcollection.zhaw.ch/handle/11475/24231
Fulltext version: Published version
License (according to publishing contract): CC BY 4.0: Attribution 4.0 International
Departement: Life Sciences and Facility Management
Organisational Unit: Institute of Chemistry and Biotechnology (ICBT)
Published as part of the ZHAW project: 3D Gewebe TEDD
Appears in collections:Publikationen Life Sciences und Facility Management

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