1. ZHAW digitalcollection
  2. School of Management and Law
  3. Publikationen
  4. Publikationen School of Management and Law
Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-26468
Full metadata record
DC FieldValueLanguage
dc.contributor.authorStebler, Rosa-
dc.contributor.authorCarmo, Luís P.-
dc.contributor.authorHeim, Dagmar-
dc.contributor.authorNaegeli, Hanspeter-
dc.contributor.authorEichler, Klaus-
dc.contributor.authorMuentener, Cedric R.-
dc.date.accessioned2022-12-20T13:21:05Z-
dc.date.available2022-12-20T13:21:05Z-
dc.date.issued2019-
dc.identifier.issn2297-1769de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/26468-
dc.description.abstractTo evaluate the contribution of antimicrobial use in human and veterinary medicine to the emergence and spread of resistant bacteria, the use of these substances has to be accurately monitored in each setting. Currently, various initiatives collect sales data of veterinary antimicrobials, thereby providing an overview of quantities on the market. However, sales data collected at the level of wholesalers or marketing authorization holders are of limited use to associate with the prevalence of bacterial resistances at species level. We converted sales data to the number of potential treatments of calves and pigs in Switzerland for the years 2011 to 2015 using animal course doses (ACD). For each authorized product, the number of potential therapies was derived from the sales at wholesaler's level and the ACD in mg per kg. For products registered for use in multiple species, a percentage of the sales was attributed to each authorized species according to their biomass distribution. We estimated a total of 5,914,349 therapies for pigs and 1,407,450 for calves in 2015. Using the number of slaughtered animals for that year as denominator, we calculated a treatment intensity of 2.15 therapies per pig and 5.96 per calf. Between 2011 and 2015, sales of veterinary antimicrobials decreased by 30%. The calculated number of potential therapies decreased by 30% for pigs and 15% for calves. An analysis of treatment intensity at antimicrobial class level showed a decrease of 64% for colistin used in pigs, and of 7% for macrolides used in both pigs and calves. Whereas the use of 3rd and 4th generation cephalosporins in calves decreased by 15.8%, usage of fluoroquinolones increased by 10.8% in the same period. Corresponding values for pigs were -16.4 and +0.7%. This is the first extrapolation of antimicrobial usage at product level for pigs and calves in Switzerland. It shows that calves were more frequently treated than pigs with a decreasing trend for both number of therapies and use of colistin, macrolides and cephalosporins 3rd and 4th generations. Nonetheless, we calculated an increase in the usage of fluoroquinolones. Altogether, this study's outcomes allow for trend analysis and can be used to assess the relationship between antimicrobial use and resistance at the national level.de_CH
dc.language.isoende_CH
dc.publisherFrontiers Research Foundationde_CH
dc.relation.ispartofFrontiers in Veterinary Sciencede_CH
dc.rightshttp://creativecommons.org/licenses/by/4.0/de_CH
dc.subjectAntibioticsde_CH
dc.subjectAntimicrobial consumptionde_CH
dc.subjectCalvede_CH
dc.subjectCourse dosede_CH
dc.subjectPigde_CH
dc.subject.ddc615: Pharmakologie und Therapeutikde_CH
dc.subject.ddc630: Landwirtschaftde_CH
dc.titleExtrapolating antibiotic sales to number of treated animals : treatments in pigs and calves in Switzerland, 2011-2015de_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementSchool of Management and Lawde_CH
zhaw.organisationalunitWinterthurer Institut für Gesundheitsökonomie (WIG)de_CH
dc.identifier.doi10.3389/fvets.2019.00318de_CH
dc.identifier.doi10.21256/zhaw-26468-
dc.identifier.pmid31616676de_CH
zhaw.funding.euNode_CH
zhaw.issue318de_CH
zhaw.originated.zhawYesde_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume6de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
Appears in collections:Publikationen School of Management and Law

Files in This Item:
File Description SizeFormat 
2019_Stebler-etal_Extrapolating-Antibiotic-Sales-to-Number-of-Treated-Animals_Forn-Vet-Sci.pdf288.29 kBAdobe PDFThumbnail
View/Open
Show simple item record
Stebler, R., Carmo, L. P., Heim, D., Naegeli, H., Eichler, K., & Muentener, C. R. (2019). Extrapolating antibiotic sales to number of treated animals : treatments in pigs and calves in Switzerland, 2011-2015. Frontiers in Veterinary Science, 6(318). https://doi.org/10.3389/fvets.2019.00318
Stebler, R. et al. (2019) ‘Extrapolating antibiotic sales to number of treated animals : treatments in pigs and calves in Switzerland, 2011-2015’, Frontiers in Veterinary Science, 6(318). Available at: https://doi.org/10.3389/fvets.2019.00318.
R. Stebler, L. P. Carmo, D. Heim, H. Naegeli, K. Eichler, and C. R. Muentener, “Extrapolating antibiotic sales to number of treated animals : treatments in pigs and calves in Switzerland, 2011-2015,” Frontiers in Veterinary Science, vol. 6, no. 318, 2019, doi: 10.3389/fvets.2019.00318.
STEBLER, Rosa, Luís P. CARMO, Dagmar HEIM, Hanspeter NAEGELI, Klaus EICHLER und Cedric R. MUENTENER, 2019. Extrapolating antibiotic sales to number of treated animals : treatments in pigs and calves in Switzerland, 2011-2015. Frontiers in Veterinary Science. 2019. Bd. 6, Nr. 318. DOI 10.3389/fvets.2019.00318
Stebler, Rosa, Luís P. Carmo, Dagmar Heim, Hanspeter Naegeli, Klaus Eichler, and Cedric R. Muentener. 2019. “Extrapolating Antibiotic Sales to Number of Treated Animals : Treatments in Pigs and Calves in Switzerland, 2011-2015.” Frontiers in Veterinary Science 6 (318). https://doi.org/10.3389/fvets.2019.00318.
Stebler, Rosa, et al. “Extrapolating Antibiotic Sales to Number of Treated Animals : Treatments in Pigs and Calves in Switzerland, 2011-2015.” Frontiers in Veterinary Science, vol. 6, no. 318, 2019, https://doi.org/10.3389/fvets.2019.00318.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.