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https://doi.org/10.21256/zhaw-26688| Publication type: | Article in scientific journal |
| Type of review: | Peer review (publication) |
| Title: | Paracelsus' legacy in the faunal realm : drugs deriving from animal toxins |
| Authors: | Fischer, Thomas Riedl, Rainer |
| et. al: | No |
| DOI: | 10.1016/j.drudis.2021.10.003 10.21256/zhaw-26688 |
| Published in: | Drug Discovery Today |
| Volume(Issue): | 27 |
| Issue: | 2 |
| Page(s): | 567 |
| Pages to: | 575 |
| Issue Date: | Feb-2022 |
| Publisher / Ed. Institution: | Elsevier |
| ISSN: | 1359-6446 1878-5832 |
| Language: | English |
| Subjects: | Animal toxin; Drug discovery; Medicinal chemistry; Natural product; Peptide; Venom; Animal; Toxin, biological; Venom |
| Subject (DDC): | 615: Pharmacology and therapeutics |
| Abstract: | Given the vast number of venomous and poisonous animals, it is surprising that only relatively few animal-derived toxins have been explored and made their way into marketed drugs or are being investigated in ongoing clinical trials. In this review, we highlight marketed drugs deriving from animal toxins as well as ongoing clinical trials and preclinical investigations in the field. We emphasize that more attention should be paid to the rich supply of candidates that nature provides as valuable starting points for addressing serious unmet medical needs. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/26688 |
| Fulltext version: | Published version |
| License (according to publishing contract): | CC BY-NC-ND 4.0: Attribution - Non commercial - No derivatives 4.0 International |
| Departement: | Life Sciences and Facility Management |
| Organisational Unit: | Institute of Chemistry and Biotechnology (ICBT) |
| Appears in collections: | Publikationen Life Sciences und Facility Management |
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| 2022_Fischer-Riedl_Paracelsus-legacy-in-the-faunal-realm_DDT.pdf | 754.25 kB | Adobe PDF |  View/Open |
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Fischer, T., & Riedl, R. (2022). Paracelsus’ legacy in the faunal realm : drugs deriving from animal toxins. Drug Discovery Today, 27(2), 567–575. https://doi.org/10.1016/j.drudis.2021.10.003
Fischer, T. and Riedl, R. (2022) ‘Paracelsus” legacy in the faunal realm : drugs deriving from animal toxins’, Drug Discovery Today, 27(2), pp. 567–575. Available at: https://doi.org/10.1016/j.drudis.2021.10.003.
T. Fischer and R. Riedl, “Paracelsus’ legacy in the faunal realm : drugs deriving from animal toxins,” Drug Discovery Today, vol. 27, no. 2, pp. 567–575, Feb. 2022, doi: 10.1016/j.drudis.2021.10.003.
FISCHER, Thomas und Rainer RIEDL, 2022. Paracelsus‘ legacy in the faunal realm : drugs deriving from animal toxins. Drug Discovery Today. Februar 2022. Bd. 27, Nr. 2, S. 567–575. DOI 10.1016/j.drudis.2021.10.003
Fischer, Thomas, and Rainer Riedl. 2022. “Paracelsus’ Legacy in the Faunal Realm : Drugs Deriving from Animal Toxins.” Drug Discovery Today 27 (2): 567–75. https://doi.org/10.1016/j.drudis.2021.10.003.
Fischer, Thomas, and Rainer Riedl. “Paracelsus’ Legacy in the Faunal Realm : Drugs Deriving from Animal Toxins.” Drug Discovery Today, vol. 27, no. 2, Feb. 2022, pp. 567–75, https://doi.org/10.1016/j.drudis.2021.10.003.
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