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Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-3417
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dc.contributor.authorAdlhart, Christian-
dc.contributor.authorVerran, Joanna-
dc.contributor.authorAzevedo, Nuno F.-
dc.contributor.authorOlmez, Hulya-
dc.contributor.authorKeinänen-Toivola, Minna M.-
dc.contributor.authorGouveia, Isabel-
dc.contributor.authorMelo, Luis F.-
dc.contributor.authorCrijns, Francy-
dc.date.accessioned2018-02-14T08:03:03Z-
dc.date.available2018-02-14T08:03:03Z-
dc.date.issued2018-
dc.identifier.issn0195-6701de_CH
dc.identifier.issn1532-2939de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/2763-
dc.description.abstractThe spread of infections in health care environments is a persistent and growing problem in most countries, aggravated by the development of microbial resistance to antibiotics and disinfectants. In addition to indwelling medical devices (implants, catheters, etc.), such infections may also result from adhesion of microbes either to external solid-water interfaces such as shower caps, taps, drains, etc, or to external solid-gas interfaces such as door handles, clothes, curtains, computer keyboards, etc. The latter are the main focus of the present work, where an overview of antimicrobial coatings for such applications is presented. The paper addresses well-established and novel methodologies, including chemical and physical functional modification of surfaces to reduce microbial contamination, as well as the potential risks associated to the implementation of such anti-contamination measures. Different chemistry-based approaches are discussed, in particular anti-adhesive surfaces (e.g., superhydrophobic, zwitterions, etc.) contact-killing surfaces (e.g., polymer brushes, phages, etc.) and biocide-releasing surfaces (e.g., triggered release, quorum sensing-based systems, etc.). The paper also assesses the impact of topographical modifications at distinct dimensions (micrometre and nanometre orders of magnitude) and the importance of applying safe-by-design criteria (toxicity, contribution for unwanted acquisition of antimicrobial resistance, long-term stability, etc.) when developing and implementing antimicrobial surfaces.de_CH
dc.language.isoende_CH
dc.publisherElsevierde_CH
dc.relation.ispartofJournal of Hospital Infectionde_CH
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/de_CH
dc.subjectHealthcare contaminationde_CH
dc.subjectAntimicrobial coatingsde_CH
dc.subjectSafe by designde_CH
dc.subject.ddc540: Chemiede_CH
dc.subject.ddc620: Ingenieurwesende_CH
dc.titleSurface modifications for antimicrobial effects in the healthcare setting : a critical overviewde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
dc.identifier.doi10.21256/zhaw-3417-
dc.identifier.doi10.1016/j.jhin.2018.01.018de_CH
dc.identifier.pmid29410096de_CH
zhaw.funding.euNode_CH
zhaw.originated.zhawYesde_CH
zhaw.publication.statusacceptedVersionde_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.webfeedFunktionsmaterialien und Nanotechnologiede_CH
Appears in collections:Publikationen Life Sciences und Facility Management

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Adlhart, C., Verran, J., Azevedo, N. F., Olmez, H., Keinänen-Toivola, M. M., Gouveia, I., Melo, L. F., & Crijns, F. (2018). Surface modifications for antimicrobial effects in the healthcare setting : a critical overview. Journal of Hospital Infection. https://doi.org/10.21256/zhaw-3417
Adlhart, C. et al. (2018) ‘Surface modifications for antimicrobial effects in the healthcare setting : a critical overview’, Journal of Hospital Infection [Preprint]. Available at: https://doi.org/10.21256/zhaw-3417.
C. Adlhart et al., “Surface modifications for antimicrobial effects in the healthcare setting : a critical overview,” Journal of Hospital Infection, 2018, doi: 10.21256/zhaw-3417.
ADLHART, Christian, Joanna VERRAN, Nuno F. AZEVEDO, Hulya OLMEZ, Minna M. KEINÄNEN-TOIVOLA, Isabel GOUVEIA, Luis F. MELO und Francy CRIJNS, 2018. Surface modifications for antimicrobial effects in the healthcare setting : a critical overview. Journal of Hospital Infection. 2018. DOI 10.21256/zhaw-3417
Adlhart, Christian, Joanna Verran, Nuno F. Azevedo, Hulya Olmez, Minna M. Keinänen-Toivola, Isabel Gouveia, Luis F. Melo, and Francy Crijns. 2018. “Surface Modifications for Antimicrobial Effects in the Healthcare Setting : A Critical Overview.” Journal of Hospital Infection. https://doi.org/10.21256/zhaw-3417.
Adlhart, Christian, et al. “Surface Modifications for Antimicrobial Effects in the Healthcare Setting : A Critical Overview.” Journal of Hospital Infection, 2018, https://doi.org/10.21256/zhaw-3417.


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