Dissemination of NDM-producing bacteria in Southern Brazil

Arend, Lavinia N.V.S.; Bergamo, Ricardo; Rocha, Fabiano B.; Bail, Larissa; Ito, Carmen; Baura, Valter A.; Balsanelli, Eduardo; Pothier, Joël F.; Rezzonico, Fabio; Pilonetto, Marcelo; Smits, Theo H.M.; Tuon, Felipe Francisco

doi:10.1016/j.diagmicrobio.2023.115930

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Dissemination of NDM-producing bacteria in Southern Brazil
Authors:	Arend, Lavinia N.V.S. Bergamo, Ricardo Rocha, Fabiano B. Bail, Larissa Ito, Carmen Baura, Valter A. Balsanelli, Eduardo Pothier, Joël F. Rezzonico, Fabio Pilonetto, Marcelo Smits, Theo H.M. Tuon, Felipe Francisco
et. al:	No
DOI:	10.1016/j.diagmicrobio.2023.115930
Published in:	Diagnostic Microbiology and Infectious Disease
Volume(Issue):	106
Issue:	2
Page(s):	115930
Issue Date:	29-Mar-2023
Publisher / Ed. Institution:	Elsevier
ISSN:	0732-8893
Language:	English
Subjects:	Carbapenemase; Plasmids; Antimicrobial resistance; Enterobacterales; Klebsiella pneumoniae
Subject (DDC):	579: Microbiology
Abstract:	Background: The dissemination of NDM-1 carbapenemases (New Delhi Metallo-β-lactamase) is a global public health problem, mainly in developing countries. The aim of this study was to characterize the spread of NDM-producing bacteria in the Southern Brazilian states analyzing epidemiological, molecular, and antimicrobial susceptibility aspects. Methods: A total of 10,684 carbapenem-resistant isolates of Enterobacterales, Pseudomonas spp. and Acinetobacter spp. obtained from several hospitals in eight cities in Southern Brazil were screened, and 486 NDM-producing bacteria were selected. Results: The incidence varied from 0.5 to 77 cases/100.000 habitants. ST11, ST15, ST340 and ST674 were the most common in K. pneumoniae. A total of five plasmids were identified in one K. pneumoniae strain: Col440I, Col440II, IncFIA(HI1), IncFIB(K), IncFIB(pQil)/ IncFII(K), and IncR. Conclusions: The number of patients with NDM-producing bacteria has increased in Southern Brazil, whose gene is present in different plasmids, explaining the expansion of this enzyme.
URI:	https://digitalcollection.zhaw.ch/handle/11475/27656
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	Life Sciences and Facility Management
Organisational Unit:	Institute of Natural Resource Sciences (IUNR)
Published as part of the ZHAW project:	Antibiotic resistances in Enterobacteria
Appears in collections:	Publikationen Life Sciences und Facility Management

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Arend, L. N. V. S., Bergamo, R., Rocha, F. B., Bail, L., Ito, C., Baura, V. A., Balsanelli, E., Pothier, J. F., Rezzonico, F., Pilonetto, M., Smits, T. H. M., & Tuon, F. F. (2023). Dissemination of NDM-producing bacteria in Southern Brazil. Diagnostic Microbiology and Infectious Disease, 106(2), 115930. https://doi.org/10.1016/j.diagmicrobio.2023.115930

Arend, L.N.V.S. et al. (2023) ‘Dissemination of NDM-producing bacteria in Southern Brazil’, Diagnostic Microbiology and Infectious Disease, 106(2), p. 115930. Available at: https://doi.org/10.1016/j.diagmicrobio.2023.115930.

L. N. V. S. Arend et al., “Dissemination of NDM-producing bacteria in Southern Brazil,” Diagnostic Microbiology and Infectious Disease, vol. 106, no. 2, p. 115930, Mar. 2023, doi: 10.1016/j.diagmicrobio.2023.115930.

AREND, Lavinia N.V.S., Ricardo BERGAMO, Fabiano B. ROCHA, Larissa BAIL, Carmen ITO, Valter A. BAURA, Eduardo BALSANELLI, Joël F. POTHIER, Fabio REZZONICO, Marcelo PILONETTO, Theo H.M. SMITS und Felipe Francisco TUON, 2023. Dissemination of NDM-producing bacteria in Southern Brazil. Diagnostic Microbiology and Infectious Disease. 29 März 2023. Bd. 106, Nr. 2, S. 115930. DOI 10.1016/j.diagmicrobio.2023.115930

Arend, Lavinia N.V.S., Ricardo Bergamo, Fabiano B. Rocha, Larissa Bail, Carmen Ito, Valter A. Baura, Eduardo Balsanelli, et al. 2023. “Dissemination of NDM-Producing Bacteria in Southern Brazil.” Diagnostic Microbiology and Infectious Disease 106 (2): 115930. https://doi.org/10.1016/j.diagmicrobio.2023.115930.

Arend, Lavinia N. V. S., et al. “Dissemination of NDM-Producing Bacteria in Southern Brazil.” Diagnostic Microbiology and Infectious Disease, vol. 106, no. 2, Mar. 2023, p. 115930, https://doi.org/10.1016/j.diagmicrobio.2023.115930.