Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-27943
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dc.contributor.advisorBrenneisen, Stephan-
dc.contributor.advisorPietsch-Schmied, Constanze-
dc.contributor.advisorVermeirssen, Etienne-
dc.contributor.advisorOlbrich, Daniel-
dc.contributor.authorOberhänsli, Silvan-
dc.date.accessioned2023-05-30T17:53:58Z-
dc.date.available2023-05-30T17:53:58Z-
dc.date.issued2023-
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/27943-
dc.description.abstractEndocrine disrupting chemicals (EDCs) are of growing concern in aquatic ecosystems due to the potential of modulating the endocrine system in aquatic species by interfering with reproduction and developmental processes. Bisphenol-A (BPA) belongs to the EDCs and has been documented to induce estrogenic effects in fish. This study aimed to develop a reliable method based on molecularly imprinted polymers solid phase extraction (SPE MIPs) and LC-MS/MS for the analysis of BPA in liver and muscle samples in invasive round goby Neogobius melanostomus sampled in the river Rhine in Basel, Switzerland. Additionally, all fish samples were analysed for the liver protein vitellogenin to provide an unspecific indication of EDC induced endocrine effects. The study also aimed to investigate any sex- and size-specific differences in BPA contamination and the overall condition of the target species, by documenting condition indicators including total length, total weight, liver weight and hepatosomatic index (HSI). BPA contamination of the sampled round goby was below limit of quantification. A further improvement of the method is needed to detect low contaminations especially in liver samples, where high matrix interferences occurred. Vitellogenin measurements indicated the presence of EDCs.de_CH
dc.format.extent67de_CH
dc.language.isoende_CH
dc.publisherZHAW Zürcher Hochschule für Angewandte Wissenschaftende_CH
dc.rightshttps://creativecommons.org/licenses/by/4.0/de_CH
dc.subjectNeogobius melanostomusde_CH
dc.subjectBisphenol-Ade_CH
dc.subjectXenoestogensde_CH
dc.subjectEndocrine Disrupting Chemicals (EDCs)de_CH
dc.subjectLC-MS/MSde_CH
dc.subjectSPE MIPsde_CH
dc.subject.ddc577: Ökologiede_CH
dc.titleAnalysis of Bisphenol-A contamination in fish liver and muscle tissue : a method development and first assessment of BPA contamination in invasive round goby Neogobius melanostomus in the Swiss Rhine river (Basel, Switzerland)de_CH
dc.typeThesis: Masterde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.publisher.placeWinterthurde_CH
dc.identifier.doi10.21256/zhaw-27943-
zhaw.originated.zhawYesde_CH
Appears in collections:Masterarbeiten Umwelt und Natürliche Ressourcen

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Oberhänsli, S. (2023). Analysis of Bisphenol-A contamination in fish liver and muscle tissue : a method development and first assessment of BPA contamination in invasive round goby Neogobius melanostomus in the Swiss Rhine river (Basel, Switzerland) [Master’s thesis, ZHAW Zürcher Hochschule für Angewandte Wissenschaften]. https://doi.org/10.21256/zhaw-27943
Oberhänsli, S. (2023) Analysis of Bisphenol-A contamination in fish liver and muscle tissue : a method development and first assessment of BPA contamination in invasive round goby Neogobius melanostomus in the Swiss Rhine river (Basel, Switzerland). Master’s thesis. ZHAW Zürcher Hochschule für Angewandte Wissenschaften. Available at: https://doi.org/10.21256/zhaw-27943.
S. Oberhänsli, “Analysis of Bisphenol-A contamination in fish liver and muscle tissue : a method development and first assessment of BPA contamination in invasive round goby Neogobius melanostomus in the Swiss Rhine river (Basel, Switzerland),” Master’s thesis, ZHAW Zürcher Hochschule für Angewandte Wissenschaften, Winterthur, 2023. doi: 10.21256/zhaw-27943.
OBERHÄNSLI, Silvan, 2023. Analysis of Bisphenol-A contamination in fish liver and muscle tissue : a method development and first assessment of BPA contamination in invasive round goby Neogobius melanostomus in the Swiss Rhine river (Basel, Switzerland). Master’s thesis. Winterthur: ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Oberhänsli, Silvan. 2023. “Analysis of Bisphenol-A Contamination in Fish Liver and Muscle Tissue : A Method Development and First Assessment of BPA Contamination in Invasive Round Goby Neogobius Melanostomus in the Swiss Rhine River (Basel, Switzerland).” Master’s thesis, Winterthur: ZHAW Zürcher Hochschule für Angewandte Wissenschaften. https://doi.org/10.21256/zhaw-27943.
Oberhänsli, Silvan. Analysis of Bisphenol-A Contamination in Fish Liver and Muscle Tissue : A Method Development and First Assessment of BPA Contamination in Invasive Round Goby Neogobius Melanostomus in the Swiss Rhine River (Basel, Switzerland). ZHAW Zürcher Hochschule für Angewandte Wissenschaften, 2023, https://doi.org/10.21256/zhaw-27943.


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