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dc.contributor.authorVahekeni, Nina-
dc.contributor.authorUrmann, Corinna-
dc.contributor.authorStehlin, Jonas-
dc.contributor.authorHofer, Niklas-
dc.contributor.authorGmach, Yvonne-
dc.contributor.authorWolfram, Evelyn-
dc.contributor.authorLardos, Andreas-
dc.date.accessioned2024-02-15T13:49:08Z-
dc.date.available2024-02-15T13:49:08Z-
dc.date.issued2023-
dc.identifier.issn0032-0943de_CH
dc.identifier.issn1439-0221de_CH
dc.identifier.urihttps://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/29926-
dc.description.abstractIn search for more effective prophylactic and curative therapeutics against SARS-CoV-2, an ethnopharmcological approach was used to select 20 plants described in the “Arzneibuch von Hallwyl” (ABvH), an influential recipe text from 16th century Switzerland. Plants were selected based on specific historical uses possibly linked with the treatment of microbial or viral infections as well as inflammatory conditions. For each plant candidate, aqueous and hydroethanolic extracts have been produced, respectively. The prophylactic activity of extracts against SARS-CoV-2 was assessed using the CellTiter-Glo​ Luminescent Cell Viability Assay upon viral infection in vitro. Four plants showed promising activity; among them Sambucus nigra L. (leaves) and Artemisia vulgaris L. (aerial parts) showed an anti-SARS-CoV-2 potential both with an activity of≤33.3 µg/mL for their hydroethanolic extract. The findings confirm the historical traditional use in the area of infectious diseases. Accordingly, this study shows supportive evidence that an ethnopharmacological approach combined with robust in vitro methods effectively enables to screen for promising antiviral plant extracts against SARS-CoV-2.de_CH
dc.language.isoende_CH
dc.publisherThiemede_CH
dc.relation.ispartofPlanta Medicade_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectSchweizde_CH
dc.subjectArzneimittelde_CH
dc.subject16. Jahrhunderde_CH
dc.subjectCovidde_CH
dc.subjectPhytopharmakologiede_CH
dc.subjectHeilpflanzede_CH
dc.subject.ddc580: Pflanzen (Botanik)de_CH
dc.subject.ddc615: Pharmakologie und Therapeutikde_CH
dc.titleHistorical herbal texts from Switzerland : a potential source for plant- derived natural products against SARS-CoV-2de_CH
dc.typeKonferenz: Posterde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
zhaw.conference.details71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Dublin, Ireland, 2–5 July 2023de_CH
zhaw.funding.euNode_CH
zhaw.issue14de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.start1422de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume89de_CH
zhaw.publication.reviewPeer review (Abstract)de_CH
zhaw.webfeedPhytopharmaziede_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
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Vahekeni, N., Urmann, C., Stehlin, J., Hofer, N., Gmach, Y., Wolfram, E., & Lardos, A. (2023). Historical herbal texts from Switzerland : a potential source for plant- derived natural products against SARS-CoV-2 [Conference poster]. Planta Medica, 89(14), 1422. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265
Vahekeni, N. et al. (2023) ‘Historical herbal texts from Switzerland : a potential source for plant- derived natural products against SARS-CoV-2’, in Planta Medica. Thieme, p. 1422. Available at: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265.
N. Vahekeni et al., “Historical herbal texts from Switzerland : a potential source for plant- derived natural products against SARS-CoV-2,” in Planta Medica, 2023, vol. 89, no. 14, p. 1422. [Online]. Available: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265
VAHEKENI, Nina, Corinna URMANN, Jonas STEHLIN, Niklas HOFER, Yvonne GMACH, Evelyn WOLFRAM und Andreas LARDOS, 2023. Historical herbal texts from Switzerland : a potential source for plant- derived natural products against SARS-CoV-2. In: Planta Medica [online]. Conference poster. Thieme. 2023. S. 1422. Verfügbar unter: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265
Vahekeni, Nina, Corinna Urmann, Jonas Stehlin, Niklas Hofer, Yvonne Gmach, Evelyn Wolfram, and Andreas Lardos. 2023. “Historical Herbal Texts from Switzerland : A Potential Source for Plant- Derived Natural Products against SARS-CoV-2.” Conference poster. In Planta Medica, 89:1422. Thieme. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265.
Vahekeni, Nina, et al. “Historical Herbal Texts from Switzerland : A Potential Source for Plant- Derived Natural Products against SARS-CoV-2.” Planta Medica, vol. 89, no. 14, Thieme, 2023, p. 1422, https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265.


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