Where does the oxygen go? : kLa measurement in bioreactors

Backoff, Tobias; Malig, Jennifer; Sören, Werner; Eibl, Dieter; John, Gernot T.

Publication type:	Contribution to magazine or newspaper
Title:	Where does the oxygen go? : kLa measurement in bioreactors
Authors:	Backoff, Tobias Malig, Jennifer Sören, Werner Eibl, Dieter John, Gernot T.
Published in:	G.I.T. Laboratory Journal
Volume(Issue):	9
Issue:	10
Page(s):	20
Pages to:	21
Issue Date:	25-Jan-2013
Publisher / Ed. Institution:	Wiley
Publisher / Ed. Institution:	Weinheim
ISSN:	1611-6038 1434-2634
Language:	English
Subject (DDC):	660: Chemical engineering
Abstract:	Small plastic tubes are available as single-use bioreactors for cell cultivation as a cost effective alternative to larger scale cultivation systems. However, the characteristics of the tubes with regard to oxygen transfer have hardly been investigated. Using a specially adapted shake flask reader (SFR) and chemical optical sensors with rapid response time, the volumetric oxygen mass transfer coefficient (kLa) for tube systems was determined. The characteristics of these cultivation vessels were investigated more closely, which represents an important step towards defined screening processes by monitoring oxygen in bioreactors.
URI:	http://www.laboratory-journal.com/applications/biological-methods/where-does-oxygen-go https://digitalcollection.zhaw.ch/handle/11475/3739
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	Life Sciences and Facility Management
Organisational Unit:	Institute of Chemistry and Biotechnology (ICBT)
Appears in collections:	Publikationen Life Sciences und Facility Management

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Backoff, T., Malig, J., Sören, W., Eibl, D., & John, G. T. (2013). Where does the oxygen go? : kLa measurement in bioreactors. G.I.T. Laboratory Journal, 9(10), 20–21. http://www.laboratory-journal.com/applications/biological-methods/where-does-oxygen-go

Backoff, T. et al. (2013) ‘Where does the oxygen go? : kLa measurement in bioreactors’, G.I.T. Laboratory Journal, 9(10), pp. 20–21. Available at: http://www.laboratory-journal.com/applications/biological-methods/where-does-oxygen-go.

T. Backoff, J. Malig, W. Sören, D. Eibl, and G. T. John, “Where does the oxygen go? : kLa measurement in bioreactors,” G.I.T. Laboratory Journal, vol. 9, no. 10, pp. 20–21, Jan. 2013, [Online]. Available: http://www.laboratory-journal.com/applications/biological-methods/where-does-oxygen-go

BACKOFF, Tobias, Jennifer MALIG, Werner SÖREN, Dieter EIBL und Gernot T. JOHN, 2013. Where does the oxygen go? : kLa measurement in bioreactors. G.I.T. Laboratory Journal [online]. 25 Januar 2013. Bd. 9, Nr. 10, S. 20–21. Verfügbar unter: http://www.laboratory-journal.com/applications/biological-methods/where-does-oxygen-go

Backoff, Tobias, Jennifer Malig, Werner Sören, Dieter Eibl, and Gernot T. John. 2013. “Where Does the Oxygen Go? : kLa Measurement in Bioreactors.” G.I.T. Laboratory Journal 9 (10): 20–21. http://www.laboratory-journal.com/applications/biological-methods/where-does-oxygen-go.

Backoff, Tobias, et al. “Where Does the Oxygen Go? : kLa Measurement in Bioreactors.” G.I.T. Laboratory Journal, vol. 9, no. 10, Jan. 2013, pp. 20–21, http://www.laboratory-journal.com/applications/biological-methods/where-does-oxygen-go.