Age difference between heterosexual partners in Britain : implications for the spread of Chlamydia trachomatis

Smid, Joost H.; Garcia, Victor; Low, Nicola; Mercer, Catherine H.; Althaus, Christian L.

doi:10.21256/zhaw-3710

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-3710

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DC Field	Value	Language
dc.contributor.author	Smid, Joost H.	-
dc.contributor.author	Garcia, Victor	-
dc.contributor.author	Low, Nicola	-
dc.contributor.author	Mercer, Catherine H.	-
dc.contributor.author	Althaus, Christian L.	-
dc.date.accessioned	2018-05-31T12:59:44Z	-
dc.date.available	2018-05-31T12:59:44Z	-
dc.date.issued	2018-03-31	-
dc.identifier.issn	1755-4365	de_CH
dc.identifier.issn	1878-0067	de_CH
dc.identifier.uri	https://digitalcollection.zhaw.ch/handle/11475/6310	-
dc.description.abstract	Heterosexual partners often differ in age. Integrating realistic patterns of sexual mixing by age into dynamic transmission models has been challenging. The effects of these patterns on the transmission of sexually transmitted infections (STI) including Chlamydia trachomatis (chlamydia), the most common bacterial STI are not well understood. We describe age mixing between new heterosexual partners using age- and sex-specific data about sexual behavior reported by people aged 16-63 years in the 2000 and 2010 British National Surveys of Sexual Attitudes and Lifestyles. We incorporate mixing patterns into a compartmental transmission model fitted to age- and sex-specific, chlamydia positivity from the same surveys, to investigate C. trachomatis transmission. We show that distributions of ages of new sex partners reported by women and by men in Britain are not consistent with each other. After balancing these distributions, new heterosexual partnerships tend to involve men who are older than women (median age difference 2, IQR -1, 5 years). We identified the most likely age combinations of heterosexual partners where incident C. trachomatis infections are generated. The model results show that in >50% of chlamydia transmitting partnerships, at least one partner is ≥25 years old. This study illustrates how sexual behavior data can be used to reconstruct detailed sexual mixing patterns by age, and how these patterns can be integrated into dynamic transmission models. The proposed framework can be extended to study the effects of age-dependent transmission on incidence in any STI.	de_CH
dc.language.iso	en	de_CH
dc.publisher	Elsevier	de_CH
dc.relation.ispartof	Epidemics	de_CH
dc.rights	http://creativecommons.org/licenses/by/4.0/	de_CH
dc.subject	Age disparity	de_CH
dc.subject	Chlamydia trachomatis	de_CH
dc.subject	Mathematical model	de_CH
dc.subject	Sexual behaviour	de_CH
dc.subject	Sexually transmitted diseases	de_CH
dc.subject.ddc	616: Innere Medizin und Krankheiten	de_CH
dc.title	Age difference between heterosexual partners in Britain : implications for the spread of Chlamydia trachomatis	de_CH
dc.type	Beitrag in wissenschaftlicher Zeitschrift	de_CH
dcterms.type	Text	de_CH
zhaw.departement	Life Sciences und Facility Management	de_CH
zhaw.organisationalunit	Institut für Computational Life Sciences (ICLS)	de_CH
dc.identifier.doi	10.21256/zhaw-3710	-
dc.identifier.doi	10.1016/j.epidem.2018.03.004	de_CH
dc.identifier.pmid	29655934	de_CH
zhaw.funding.eu	No	de_CH
zhaw.originated.zhaw	No	de_CH
zhaw.pages.end	66	de_CH
zhaw.pages.start	60	de_CH
zhaw.publication.status	publishedVersion	de_CH
zhaw.volume	24	de_CH
zhaw.publication.review	Peer review (Publikation)	de_CH
zhaw.webfeed	Applied Mathematical Biology	de_CH
Appears in collections:	Publikationen Life Sciences und Facility Management

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Smid, J. H., Garcia, V., Low, N., Mercer, C. H., & Althaus, C. L. (2018). Age difference between heterosexual partners in Britain : implications for the spread of Chlamydia trachomatis. Epidemics, 24, 60–66. https://doi.org/10.21256/zhaw-3710

Smid, J.H. et al. (2018) ‘Age difference between heterosexual partners in Britain : implications for the spread of Chlamydia trachomatis’, Epidemics, 24, pp. 60–66. Available at: https://doi.org/10.21256/zhaw-3710.

J. H. Smid, V. Garcia, N. Low, C. H. Mercer, and C. L. Althaus, “Age difference between heterosexual partners in Britain : implications for the spread of Chlamydia trachomatis,” Epidemics, vol. 24, pp. 60–66, Mar. 2018, doi: 10.21256/zhaw-3710.

SMID, Joost H., Victor GARCIA, Nicola LOW, Catherine H. MERCER und Christian L. ALTHAUS, 2018. Age difference between heterosexual partners in Britain : implications for the spread of Chlamydia trachomatis. Epidemics. 31 März 2018. Bd. 24, S. 60–66. DOI 10.21256/zhaw-3710

Smid, Joost H., Victor Garcia, Nicola Low, Catherine H. Mercer, and Christian L. Althaus. 2018. “Age Difference between Heterosexual Partners in Britain : Implications for the Spread of Chlamydia Trachomatis.” Epidemics 24 (March): 60–66. https://doi.org/10.21256/zhaw-3710.

Smid, Joost H., et al. “Age Difference between Heterosexual Partners in Britain : Implications for the Spread of Chlamydia Trachomatis.” Epidemics, vol. 24, Mar. 2018, pp. 60–66, https://doi.org/10.21256/zhaw-3710.