Galactosyltransferase — still up and running

Berger, Eric G.; Rohrer, Jack

doi:10.1016/S0300-9084(03)00008-7

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Galactosyltransferase — still up and running
Authors:	Berger, Eric G. Rohrer, Jack
DOI:	10.1016/S0300-9084(03)00008-7
Published in:	Biochimie
Volume(Issue):	85
Issue:	3-4
Page(s):	261
Pages to:	274
Issue Date:	Mar-2003
Publisher / Ed. Institution:	Elsevier
ISSN:	0300-9084
Language:	English
Subject (DDC):	572: Biochemistry
Abstract:	The following review on galactosyltransferase (gal-T1) intends to cover genetic, biochemical, structural, biotechnological, cell biological and medical aspects of this enzyme in a comprehensive manner from discovery to the present day which have brought to light a genetic defect of this enzyme. Early work has only been included if it appeared relevant to ongoing issues. Following the evolution of a research topic over 40 years is in itself a fascinating endeavour as it permits to observe the ins and outs of hypotheses, fashions and errors. Gal-T1 is a beautiful example as it has been involved in almost every aspect of life science. Importantly, there is a future to this enzyme as a research topic, since many questions still remain unanswered: to which extent is it a representative Golgi protein? What is the role of the gene family of gal-Ts? Does gal-T1 exert any functions other than a catalytic one? Why is it phosphorylated? Does it form homodimers in vivo? Surely, there is room for further work, which is likely to reveal further insights into cellular trafficking and signaling and, in the context of the gene family, shall contribute to understanding development and morphogenesis.
URI:	https://digitalcollection.zhaw.ch/handle/11475/6797
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	Life Sciences and Facility Management
Organisational Unit:	Institute of Chemistry and Biotechnology (ICBT)
Appears in collections:	Publikationen Life Sciences und Facility Management

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Berger, E. G., & Rohrer, J. (2003). Galactosyltransferase — still up and running. Biochimie, 85(3-4), 261–274. https://doi.org/10.1016/S0300-9084(03)00008-7

Berger, E.G. and Rohrer, J. (2003) ‘Galactosyltransferase — still up and running’, Biochimie, 85(3-4), pp. 261–274. Available at: https://doi.org/10.1016/S0300-9084(03)00008-7.

E. G. Berger and J. Rohrer, “Galactosyltransferase — still up and running,” Biochimie, vol. 85, no. 3-4, pp. 261–274, Mar. 2003, doi: 10.1016/S0300-9084(03)00008-7.

BERGER, Eric G. und Jack ROHRER, 2003. Galactosyltransferase — still up and running. Biochimie. März 2003. Bd. 85, Nr. 3-4, S. 261–274. DOI 10.1016/S0300-9084(03)00008-7

Berger, Eric G., and Jack Rohrer. 2003. “Galactosyltransferase — Still up and Running.” Biochimie 85 (3-4): 261–74. https://doi.org/10.1016/S0300-9084(03)00008-7.

Berger, Eric G., and Jack Rohrer. “Galactosyltransferase — Still up and Running.” Biochimie, vol. 85, no. 3-4, Mar. 2003, pp. 261–74, https://doi.org/10.1016/S0300-9084(03)00008-7.