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Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-5505
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dc.contributor.authorJonsdottir, Hulda R.-
dc.contributor.authorDelaval, Mathilde-
dc.contributor.authorLeni, Zaira-
dc.contributor.authorKeller, Alejandro-
dc.contributor.authorBrem, Benjamin T.-
dc.contributor.authorSiegerist, Frithjof-
dc.contributor.authorSchönenberger, David-
dc.contributor.authorDurdina, Lukas-
dc.contributor.authorElser, Miriam-
dc.contributor.authorBurtscher, Heinz-
dc.contributor.authorLiati, Anthi-
dc.contributor.authorGeiser, Marianne-
dc.date.accessioned2019-03-15T13:47:16Z-
dc.date.available2019-03-15T13:47:16Z-
dc.date.issued2019-
dc.identifier.issn2399-3642de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/16116-
dc.description.abstractAircraft emissions contribute to local and global air pollution. Health effects of particulate matter (PM) from aircraft engines are largely unknown, since controlled cell exposures at relevant conditions are challenging. We examined the toxicity of non-volatile PM (nvPM) emissions from a CFM56-7B26 turbofan, the world's most used aircraft turbine using an unprecedented exposure setup. We combined direct turbine-exhaust sampling under realistic engine operating conditions and the Nano-Aerosol Chamber for In vitro Toxicity to deposit particles onto air-liquid-interface cultures of human bronchial epithelial cells (BEAS-2B) at physiological conditions. We evaluated acute cellular responses after 1-h exposures to diluted exhaust from conventional or alternative fuel combustion. We show that single, short-term exposures to nvPM impair bronchial epithelial cells, and PM from conventional fuel at ground-idle conditions is the most hazardous. Electron microscopy of soot reveals varying reactivity matching the observed cellular responses. Stronger responses at lower mass concentrations suggest that additional metrics are necessary to evaluate health risks of this increasingly important emission source.de_CH
dc.language.isoende_CH
dc.publisherNature Publishing Groupde_CH
dc.relation.ispartofCommunications Biologyde_CH
dc.rightshttp://creativecommons.org/licenses/by/4.0/de_CH
dc.subjectMechanisms of diseasede_CH
dc.subjectRespiratory tract diseasesde_CH
dc.subject.ddc363: Umwelt- und Sicherheitsproblemede_CH
dc.titleNon-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cellsde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementSchool of Engineeringde_CH
zhaw.organisationalunitZentrum für Aviatik (ZAV)de_CH
dc.identifier.doi10.21256/zhaw-5505-
dc.identifier.doi10.1038/s42003-019-0332-7de_CH
dc.identifier.pmid30854482de_CH
zhaw.funding.euNode_CH
zhaw.issue90de_CH
zhaw.originated.zhawYesde_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume2de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.webfeedMeteorology, Environment and Air Traffic (ZAV)de_CH
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Jonsdottir, H. R., Delaval, M., Leni, Z., Keller, A., Brem, B. T., Siegerist, F., Schönenberger, D., Durdina, L., Elser, M., Burtscher, H., Liati, A., & Geiser, M. (2019). Non-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cells. Communications Biology, 2(90). https://doi.org/10.21256/zhaw-5505
Jonsdottir, H.R. et al. (2019) ‘Non-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cells’, Communications Biology, 2(90). Available at: https://doi.org/10.21256/zhaw-5505.
H. R. Jonsdottir et al., “Non-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cells,” Communications Biology, vol. 2, no. 90, 2019, doi: 10.21256/zhaw-5505.
JONSDOTTIR, Hulda R., Mathilde DELAVAL, Zaira LENI, Alejandro KELLER, Benjamin T. BREM, Frithjof SIEGERIST, David SCHÖNENBERGER, Lukas DURDINA, Miriam ELSER, Heinz BURTSCHER, Anthi LIATI und Marianne GEISER, 2019. Non-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cells. Communications Biology. 2019. Bd. 2, Nr. 90. DOI 10.21256/zhaw-5505
Jonsdottir, Hulda R., Mathilde Delaval, Zaira Leni, Alejandro Keller, Benjamin T. Brem, Frithjof Siegerist, David Schönenberger, et al. 2019. “Non-Volatile Particle Emissions from Aircraft Turbine Engines at Ground-Idle Induce Oxidative Stress in Bronchial Cells.” Communications Biology 2 (90). https://doi.org/10.21256/zhaw-5505.
Jonsdottir, Hulda R., et al. “Non-Volatile Particle Emissions from Aircraft Turbine Engines at Ground-Idle Induce Oxidative Stress in Bronchial Cells.” Communications Biology, vol. 2, no. 90, 2019, https://doi.org/10.21256/zhaw-5505.


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