| Publication type: | Article in scientific journal |
| Type of review: | Peer review (publication) |
| Title: | Simulated moving bed chromatography : the next step in HPLC |
| Authors: | van Oordt, Thomas Bayliss, Edwin Netscher, Thomas Bonrath, Werner Spielmann, Thomas |
| DOI: | 10.2533/000942906777674967 |
| Published in: | Chimia |
| Volume(Issue): | 60 |
| Issue: | 3 |
| Page(s): | 150 |
| Pages to: | 152 |
| Issue Date: | 2006 |
| Publisher / Ed. Institution: | Schweizerische Chemische Gesellschaft |
| ISSN: | 0009-4293 |
| Language: | English |
| Subjects: | Preparative Chromatography; Simulated Moving Bed; Tocopherols; Tocotrienols; Vitamin E |
| Subject (DDC): | 660: Chemical engineering |
| Abstract: | Simulated Moving Bed (SMB) technology, a continuous chromatographic separation process, is of increasing interest in the field of pharmaceuticals, fine chemicals, and biotechnology. The complexity of SMB asks for a deeper understanding of the mathematical design and physical adsorption processes, along with the practical training in chromatography and process engineering. This makes SMB a technology which is also suitable for educational purposes. The principle of SMB separation is described with a short introduction of its mathematical design for a simulation. A method of measuring the adsorption isotherms, which are crucial for a process simulation, is also discussed. As an example, the application of SMB to the separation of two groups of biologically important vitamin E compounds, i.e. tocopherols and tocotrienols from natural-source material is presented. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/16232 |
| Fulltext version: | Published version |
| License (according to publishing contract): | Licence according to publishing contract |
| Departement: | School of Engineering |
| Organisational Unit: | Institute of Materials and Process Engineering (IMPE) |
| Appears in collections: | Publikationen School of Engineering |
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van Oordt, T., Bayliss, E., Netscher, T., Bonrath, W., & Spielmann, T. (2006). Simulated moving bed chromatography : the next step in HPLC. Chimia, 60(3), 150–152. https://doi.org/10.2533/000942906777674967
van Oordt, T. et al. (2006) ‘Simulated moving bed chromatography : the next step in HPLC’, Chimia, 60(3), pp. 150–152. Available at: https://doi.org/10.2533/000942906777674967.
T. van Oordt, E. Bayliss, T. Netscher, W. Bonrath, and T. Spielmann, “Simulated moving bed chromatography : the next step in HPLC,” Chimia, vol. 60, no. 3, pp. 150–152, 2006, doi: 10.2533/000942906777674967.
VAN OORDT, Thomas, Edwin BAYLISS, Thomas NETSCHER, Werner BONRATH und Thomas SPIELMANN, 2006. Simulated moving bed chromatography : the next step in HPLC. Chimia. 2006. Bd. 60, Nr. 3, S. 150–152. DOI 10.2533/000942906777674967
van Oordt, Thomas, Edwin Bayliss, Thomas Netscher, Werner Bonrath, and Thomas Spielmann. 2006. “Simulated Moving Bed Chromatography : The next Step in HPLC.” Chimia 60 (3): 150–52. https://doi.org/10.2533/000942906777674967.
van Oordt, Thomas, et al. “Simulated Moving Bed Chromatography : The next Step in HPLC.” Chimia, vol. 60, no. 3, 2006, pp. 150–52, https://doi.org/10.2533/000942906777674967.
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