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  4. Publikationen School of Engineering
Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-20461
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dc.contributor.authorBabity, Samuel-
dc.contributor.authorPolomska, Anna K.-
dc.contributor.authorCouture, Frédéric-
dc.contributor.authorBonmarin, Mathias-
dc.contributor.authorFehr, Daniel-
dc.contributor.authorDetmar, Michael-
dc.contributor.authorBrambilla, Davide-
dc.date.accessioned2020-09-10T16:59:30Z-
dc.date.available2020-09-10T16:59:30Z-
dc.date.issued2020-08-18-
dc.identifier.issn0168-3659de_CH
dc.identifier.issn1873-4995de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/20461-
dc.description.abstractThe monitoring of lymphatic drainage is of great importance, particularly in the context of the early detection and diagnosis of several diseases. Existing methods of imaging and monitoring lymphatic drainage can be costly and require trained personnel, posing problems for at-home or point-of-care monitoring. Recently, an alternative approach has been proposed, consisting of using microneedles to deliver a near-infrared (NIR) fluorescent tattoo to the skin, which can be monitored with traditional laboratory-based fluorescence detectors. In this work, we present further development of this approach, using a specifically designed NIR-fluorescent probe and rational optimization of microneedle properties and the spatial location of the NIR dye within the microneedles. Moreover, we demonstrate that this method is compatible with a custom-made portable fluorescence measurement device and able to discriminate between drainage and lack of drainage in vivo in rats.de_CH
dc.language.isoende_CH
dc.publisherElsevierde_CH
dc.relation.ispartofJournal of Controlled Releasede_CH
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/de_CH
dc.subjectDiagnosticsde_CH
dc.subjectLymphaticsde_CH
dc.subjectMicroneedlede_CH
dc.subjectMonitoringde_CH
dc.subjectTattoode_CH
dc.subject.ddc610: Medizin und Gesundheitde_CH
dc.titleRational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic functionde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementSchool of Engineeringde_CH
zhaw.organisationalunitInstitute of Computational Physics (ICP)de_CH
dc.identifier.doi10.1016/j.jconrel.2020.08.017de_CH
dc.identifier.doi10.21256/zhaw-20461-
dc.identifier.pmid32818560de_CH
zhaw.funding.euNode_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end359de_CH
zhaw.pages.start350de_CH
zhaw.publication.statusacceptedVersionde_CH
zhaw.volume327de_CH
zhaw.embargo.end2021-08-18de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.webfeedSensors and Measuring Systemsde_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
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Babity, S., Polomska, A. K., Couture, F., Bonmarin, M., Fehr, D., Detmar, M., & Brambilla, D. (2020). Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function. Journal of Controlled Release, 327, 350–359. https://doi.org/10.1016/j.jconrel.2020.08.017
Babity, S. et al. (2020) ‘Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function’, Journal of Controlled Release, 327, pp. 350–359. Available at: https://doi.org/10.1016/j.jconrel.2020.08.017.
S. Babity et al., “Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function,” Journal of Controlled Release, vol. 327, pp. 350–359, Aug. 2020, doi: 10.1016/j.jconrel.2020.08.017.
BABITY, Samuel, Anna K. POLOMSKA, Frédéric COUTURE, Mathias BONMARIN, Daniel FEHR, Michael DETMAR und Davide BRAMBILLA, 2020. Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function. Journal of Controlled Release. 18 August 2020. Bd. 327, S. 350–359. DOI 10.1016/j.jconrel.2020.08.017
Babity, Samuel, Anna K. Polomska, Frédéric Couture, Mathias Bonmarin, Daniel Fehr, Michael Detmar, and Davide Brambilla. 2020. “Rational Design of a Fluorescent Microneedle Tattoo for Minimally Invasive Monitoring of Lymphatic Function.” Journal of Controlled Release 327 (August): 350–59. https://doi.org/10.1016/j.jconrel.2020.08.017.
Babity, Samuel, et al. “Rational Design of a Fluorescent Microneedle Tattoo for Minimally Invasive Monitoring of Lymphatic Function.” Journal of Controlled Release, vol. 327, Aug. 2020, pp. 350–59, https://doi.org/10.1016/j.jconrel.2020.08.017.


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