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dc.contributor.authorSpiess, Martina R.-
dc.contributor.authorMüller, Roland M.-
dc.contributor.authorRupp, Rüdiger-
dc.contributor.authorSchuld, Christian-
dc.contributor.authorvan Hedel, Hubertus-
dc.date.accessioned2022-09-08T10:22:35Z-
dc.date.available2022-09-08T10:22:35Z-
dc.date.issued2009-11-
dc.identifier.issn0897-7151de_CH
dc.identifier.issn1557-9042de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/25606-
dc.description.abstractThe neurological severity of a spinal cord injury (SCI) is commonly classified according to the American Spinal Injury Association (ASIA) Impairment Scale (AIS). The aim of this study was to assess the course of the AIS following SCI, and to discern the nature of any changes in the classification that occur. Assessments were performed in a European cohort of SCI patients within 2 weeks and at 1, 3, 6, and 12 months after the initial injury. Overall, about 70% of the patients initially diagnosed as AIS A did not convert, as did 90% of the AIS D patients. When only evaluating patients with complete datasets, 68% did not convert, while the AIS category improved in 30% of patients and deteriorated in 2%. A change in the last sacral segments (40%), motor improvement (31%), sensory improvement (19%), and a change in the neurological level of the SCI (10%) contributed to or accompanied the AIS conversion. When the AIS remained unchanged between successive assessment points, there was no change in the number of muscles graded three or more (NMG3(+)) in 73% of the transitions. An improvement in AIS was associated with a gain in NMG3(+) in 49% of the transitions, while an aggravation in AIS was accompanied by a loss in NMG3(+) in 10% of the transitions. These results, documenting a substantial amount of spontaneous AIS conversions, should be taken into consideration when designing clinical trials to assess the effects of potential new treatments for SCI.de_CH
dc.language.isoende_CH
dc.publisherMary Ann Liebertde_CH
dc.relation.ispartofJournal of Neurotraumade_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectHumansde_CH
dc.subjectSpinal cord injuryde_CH
dc.subjectTime factorde_CH
dc.subjectRecovery of functionde_CH
dc.subjectSeverity of illness indexde_CH
dc.subject.ddc616.8: Neurologie und Krankheiten des Nervensystemsde_CH
dc.subject.ddc617: Chirurgiede_CH
dc.titleConversion in ASIA impairment scale during the first year after traumatic spinal cord injuryde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementGesundheitde_CH
zhaw.organisationalunitInstitut für Ergotherapie (IER)de_CH
dc.identifier.doi10.1089/neu.2008.0760de_CH
dc.identifier.pmid19456213de_CH
zhaw.funding.euNode_CH
zhaw.issue11de_CH
zhaw.originated.zhawNode_CH
zhaw.pages.end2036de_CH
zhaw.pages.start2027de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume26de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
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Spiess, M. R., Müller, R. M., Rupp, R., Schuld, C., & van Hedel, H. (2009). Conversion in ASIA impairment scale during the first year after traumatic spinal cord injury. Journal of Neurotrauma, 26(11), 2027–2036. https://doi.org/10.1089/neu.2008.0760
Spiess, M.R. et al. (2009) ‘Conversion in ASIA impairment scale during the first year after traumatic spinal cord injury’, Journal of Neurotrauma, 26(11), pp. 2027–2036. Available at: https://doi.org/10.1089/neu.2008.0760.
M. R. Spiess, R. M. Müller, R. Rupp, C. Schuld, and H. van Hedel, “Conversion in ASIA impairment scale during the first year after traumatic spinal cord injury,” Journal of Neurotrauma, vol. 26, no. 11, pp. 2027–2036, Nov. 2009, doi: 10.1089/neu.2008.0760.
SPIESS, Martina R., Roland M. MÜLLER, Rüdiger RUPP, Christian SCHULD und Hubertus VAN HEDEL, 2009. Conversion in ASIA impairment scale during the first year after traumatic spinal cord injury. Journal of Neurotrauma. November 2009. Bd. 26, Nr. 11, S. 2027–2036. DOI 10.1089/neu.2008.0760
Spiess, Martina R., Roland M. Müller, Rüdiger Rupp, Christian Schuld, and Hubertus van Hedel. 2009. “Conversion in ASIA Impairment Scale during the First Year after Traumatic Spinal Cord Injury.” Journal of Neurotrauma 26 (11): 2027–36. https://doi.org/10.1089/neu.2008.0760.
Spiess, Martina R., et al. “Conversion in ASIA Impairment Scale during the First Year after Traumatic Spinal Cord Injury.” Journal of Neurotrauma, vol. 26, no. 11, Nov. 2009, pp. 2027–36, https://doi.org/10.1089/neu.2008.0760.


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