Influencing factors on instrumental activities of daily living functioning in people with mild cognitive disorder : a secondary investigation of cross-sectional data

Bruderer-Hofstetter, Marina; Gorus, Ellen; Cornelis, Elise; Meichtry, André; De Vriendt, Patricia

doi:10.1186/s12877-022-03476-8

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-26477

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Influencing factors on instrumental activities of daily living functioning in people with mild cognitive disorder : a secondary investigation of cross-sectional data
Authors:	Bruderer-Hofstetter, Marina Gorus, Ellen Cornelis, Elise Meichtry, André De Vriendt, Patricia
et. al:	No
DOI:	10.1186/s12877-022-03476-8 10.21256/zhaw-26477
Published in:	BMC Geriatrics
Volume(Issue):	22
Issue:	1
Page(s):	791
Issue Date:	2022
Publisher / Ed. Institution:	BioMed Central
ISSN:	1471-2318
Language:	English
Subjects:	Cognitive function; Instrumental activity of daily living; Mild neurocognitive disorder; Personal and environmental factor; Physical function; Activities of daily living; Aged, 80 and over; Cognition; Cross-sectional study; Female; Human; Male; Neuropsychological test; Cognitive dysfunction; Dementia
Subject (DDC):	615.82: Physical therapy 616.8: Neurology, diseases of nervous system
Abstract:	Background: Finding a strategy to reduce the impact of cognitive decline on everyday functioning in persons suffering from cognitive impairment is a public health priority. Instrumental activities of daily living (IADL) are key to everyday functioning. Hence, it is essential to understand the influencing factors on IADL to develop specific interventions to improve everyday functioning in persons with mild cognitive disorder. Therefore, this study aimed to 1) explore different influencing factors on IADL functioning considering all domains of the International Classification of Functioning, disability, and health and 2) rank these factors. Methods: We performed a secondary analysis of a cohort including participants with amnestic mild cognitive impairment (a-MCI) or mild Alzheimer’s Dementia (mild AD). The IADL functioning model was used as a starting point to estimate the effects of cognitive and physical function factors and personal and environmental factors on IADL functioning using multiple linear regression analysis, including subgroup analysis in persons with a-MCI. We used standardized coefficient estimates to relate the size of the predictor effects in the final model. Results: We included 105 participants (64 a-MCI, 41 mild AD); the mean age was 81.9 years (SD 4.9), with 70% females. Based on a multi-step approach and model fit, the final model included IADL functioning as the response variable and memory, attention, executive function, vision and hearing, mobility, balance, education, and social support as predictors. The final model explained 75% of the variability. The significant predictors in the model were mobility, balance, attention, and education, and were the predictors with the most considerable effects based on standardized coefficient estimates. The subgroup analysis, including only a-MCI participants, revealed a similar pattern. Conclusion: Our results confirm that IADL functioning in people with mild cognitive disorder is influenced by cognitive and physical function and personal factors. The study provides further insight into understanding IADL functioning impairments in persons with mild impaired cognition and may be used to develop specific non-pharmacological interventions.
URI:	https://digitalcollection.zhaw.ch/handle/11475/26477
Fulltext version:	Published version
License (according to publishing contract):	CC BY 4.0: Attribution 4.0 International
Departement:	School of Health Sciences
Organisational Unit:	Institute of Physiotherapy (IPT)
Appears in collections:	Publikationen Gesundheit

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Bruderer-Hofstetter, M., Gorus, E., Cornelis, E., Meichtry, A., & De Vriendt, P. (2022). Influencing factors on instrumental activities of daily living functioning in people with mild cognitive disorder : a secondary investigation of cross-sectional data. BMC Geriatrics, 22(1), 791. https://doi.org/10.1186/s12877-022-03476-8

Bruderer-Hofstetter, M. et al. (2022) ‘Influencing factors on instrumental activities of daily living functioning in people with mild cognitive disorder : a secondary investigation of cross-sectional data’, BMC Geriatrics, 22(1), p. 791. Available at: https://doi.org/10.1186/s12877-022-03476-8.

M. Bruderer-Hofstetter, E. Gorus, E. Cornelis, A. Meichtry, and P. De Vriendt, “Influencing factors on instrumental activities of daily living functioning in people with mild cognitive disorder : a secondary investigation of cross-sectional data,” BMC Geriatrics, vol. 22, no. 1, p. 791, 2022, doi: 10.1186/s12877-022-03476-8.

BRUDERER-HOFSTETTER, Marina, Ellen GORUS, Elise CORNELIS, André MEICHTRY und Patricia DE VRIENDT, 2022. Influencing factors on instrumental activities of daily living functioning in people with mild cognitive disorder : a secondary investigation of cross-sectional data. BMC Geriatrics. 2022. Bd. 22, Nr. 1, S. 791. DOI 10.1186/s12877-022-03476-8

Bruderer-Hofstetter, Marina, Ellen Gorus, Elise Cornelis, André Meichtry, and Patricia De Vriendt. 2022. “Influencing Factors on Instrumental Activities of Daily Living Functioning in People with Mild Cognitive Disorder : A Secondary Investigation of Cross-Sectional Data.” BMC Geriatrics 22 (1): 791. https://doi.org/10.1186/s12877-022-03476-8.

Bruderer-Hofstetter, Marina, et al. “Influencing Factors on Instrumental Activities of Daily Living Functioning in People with Mild Cognitive Disorder : A Secondary Investigation of Cross-Sectional Data.” BMC Geriatrics, vol. 22, no. 1, 2022, p. 791, https://doi.org/10.1186/s12877-022-03476-8.