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https://doi.org/10.21256/zhaw-27789| Publication type: | Article in scientific journal |
| Type of review: | Peer review (publication) |
| Title: | Portable multi-wavelength fluorescence measurement device : empirical evaluation |
| Authors: | Hagen, Raphael Fehr, Daniel Spano, Fabrizio Babity, Samuel Brambilla, Davide Bonmarin, Mathias |
| et. al: | No |
| DOI: | 10.1109/TIM.2023.3270999 10.21256/zhaw-27789 |
| Published in: | IEEE Transactions on Instrumentation and Measurement |
| Volume(Issue): | 72 |
| Issue: | 4005409 |
| Issue Date: | 2023 |
| Publisher / Ed. Institution: | IEEE |
| ISSN: | 0018-9456 1557-9662 |
| Language: | English |
| Subjects: | Fluorescence meter; Ratiometric fluorescent tattoo; Fluorometer; Portable; Handheld; Multi-wavelength |
| Subject (DDC): | 620: Engineering |
| Abstract: | Monitoring-based preventive medicine relies heavily on minimal or noninvasive, portable, and cost-effective measurement solutions. In this study, we present a handheld multiwavelength fluorescence measurement system for detection of dermally injected fluorescent tracers. The circular detection area of the device is positioned on the sample containing the fluorescent marker. The marker is excited at regular intervals by a pulse of light. The optical output power is controlled by a laser diode driver, which receives direct feedback on the emitted light intensity from the monitor photodiode integrated into the laser diode package. An optical diffuser is located in front of each laser diode to ensure uniform illumination of the measurement area. Pulsed excitation of the fluorescent tracer allows alternate measurement of foreground and background light intensity. By subtracting the background from the foreground and using a switched-input photocurrent measurement technique, the measured photocurrent represents the actual light emission from the marker. The instrument has interchangeable modules that contain the excitation electronics and emission filter. These modules allow the instrument to be configured for a variety of different fluorescent markers. In vitro measurements show that the device is capable of performing fluorescence measurements for its intended use as a point-of-care device in preventive medicine. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/27789 |
| Fulltext version: | Accepted version |
| License (according to publishing contract): | Licence according to publishing contract |
| Departement: | School of Engineering |
| Organisational Unit: | Institute of Computational Physics (ICP) |
| Appears in collections: | Publikationen School of Engineering |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2023_Hagen-etal_Portable-multi-wavelength-fluorescence-measurement-device-empirical_evaluation_AAM_IEEE.pdf | Accepted Version | 3.51 MB | Adobe PDF |  View/Open |
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Hagen, R., Fehr, D., Spano, F., Babity, S., Brambilla, D., & Bonmarin, M. (2023). Portable multi-wavelength fluorescence measurement device : empirical evaluation. IEEE Transactions on Instrumentation and Measurement, 72(4005409). https://doi.org/10.1109/TIM.2023.3270999
Hagen, R. et al. (2023) ‘Portable multi-wavelength fluorescence measurement device : empirical evaluation’, IEEE Transactions on Instrumentation and Measurement, 72(4005409). Available at: https://doi.org/10.1109/TIM.2023.3270999.
R. Hagen, D. Fehr, F. Spano, S. Babity, D. Brambilla, and M. Bonmarin, “Portable multi-wavelength fluorescence measurement device : empirical evaluation,” IEEE Transactions on Instrumentation and Measurement, vol. 72, no. 4005409, 2023, doi: 10.1109/TIM.2023.3270999.
HAGEN, Raphael, Daniel FEHR, Fabrizio SPANO, Samuel BABITY, Davide BRAMBILLA und Mathias BONMARIN, 2023. Portable multi-wavelength fluorescence measurement device : empirical evaluation. IEEE Transactions on Instrumentation and Measurement. 2023. Bd. 72, Nr. 4005409. DOI 10.1109/TIM.2023.3270999
Hagen, Raphael, Daniel Fehr, Fabrizio Spano, Samuel Babity, Davide Brambilla, and Mathias Bonmarin. 2023. “Portable Multi-Wavelength Fluorescence Measurement Device : Empirical Evaluation.” IEEE Transactions on Instrumentation and Measurement 72 (4005409). https://doi.org/10.1109/TIM.2023.3270999.
Hagen, Raphael, et al. “Portable Multi-Wavelength Fluorescence Measurement Device : Empirical Evaluation.” IEEE Transactions on Instrumentation and Measurement, vol. 72, no. 4005409, 2023, https://doi.org/10.1109/TIM.2023.3270999.
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