Analysis of Bisphenol-A contamination in fish liver and muscle tissue : a method development and first assessment of BPA contamination in invasive round goby Neogobius melanostomus in the Swiss Rhine river (Basel, Switzerland)

Oberhänsli, Silvan

doi:10.21256/zhaw-27943

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-27943

Publication type:	Master thesis
Title:	Analysis of Bisphenol-A contamination in fish liver and muscle tissue : a method development and first assessment of BPA contamination in invasive round goby Neogobius melanostomus in the Swiss Rhine river (Basel, Switzerland)
Authors:	Oberhänsli, Silvan
Advisors / Reviewers:	Brenneisen, Stephan Pietsch-Schmied, Constanze Vermeirssen, Etienne Olbrich, Daniel
DOI:	10.21256/zhaw-27943
Extent:	67
Issue Date:	2023
Publisher / Ed. Institution:	ZHAW Zürcher Hochschule für Angewandte Wissenschaften
Publisher / Ed. Institution:	Winterthur
Language:	English
Subjects:	Neogobius melanostomus; Bisphenol-A; Xenoestogens; Endocrine Disrupting Chemicals (EDCs); LC-MS/MS; SPE MIPs
Subject (DDC):	577: Ecology
Abstract:	Endocrine disrupting chemicals (EDCs) are of growing concern in aquatic ecosystems due to the potential of modulating the endocrine system in aquatic species by interfering with reproduction and developmental processes. Bisphenol-A (BPA) belongs to the EDCs and has been documented to induce estrogenic effects in fish. This study aimed to develop a reliable method based on molecularly imprinted polymers solid phase extraction (SPE MIPs) and LC-MS/MS for the analysis of BPA in liver and muscle samples in invasive round goby Neogobius melanostomus sampled in the river Rhine in Basel, Switzerland. Additionally, all fish samples were analysed for the liver protein vitellogenin to provide an unspecific indication of EDC induced endocrine effects. The study also aimed to investigate any sex- and size-specific differences in BPA contamination and the overall condition of the target species, by documenting condition indicators including total length, total weight, liver weight and hepatosomatic index (HSI). BPA contamination of the sampled round goby was below limit of quantification. A further improvement of the method is needed to detect low contaminations especially in liver samples, where high matrix interferences occurred. Vitellogenin measurements indicated the presence of EDCs.
URI:	https://digitalcollection.zhaw.ch/handle/11475/27943
License (according to publishing contract):	CC BY 4.0: Attribution 4.0 International
Departement:	Life Sciences and Facility Management
Appears in collections:	Masterarbeiten Umwelt und Natürliche Ressourcen

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Oberhänsli, S. (2023). Analysis of Bisphenol-A contamination in fish liver and muscle tissue : a method development and first assessment of BPA contamination in invasive round goby Neogobius melanostomus in the Swiss Rhine river (Basel, Switzerland) [Master’s thesis, ZHAW Zürcher Hochschule für Angewandte Wissenschaften]. https://doi.org/10.21256/zhaw-27943

Oberhänsli, S. (2023) Analysis of Bisphenol-A contamination in fish liver and muscle tissue : a method development and first assessment of BPA contamination in invasive round goby Neogobius melanostomus in the Swiss Rhine river (Basel, Switzerland). Master’s thesis. ZHAW Zürcher Hochschule für Angewandte Wissenschaften. Available at: https://doi.org/10.21256/zhaw-27943.

S. Oberhänsli, “Analysis of Bisphenol-A contamination in fish liver and muscle tissue : a method development and first assessment of BPA contamination in invasive round goby Neogobius melanostomus in the Swiss Rhine river (Basel, Switzerland),” Master’s thesis, ZHAW Zürcher Hochschule für Angewandte Wissenschaften, Winterthur, 2023. doi: 10.21256/zhaw-27943.

OBERHÄNSLI, Silvan, 2023. Analysis of Bisphenol-A contamination in fish liver and muscle tissue : a method development and first assessment of BPA contamination in invasive round goby Neogobius melanostomus in the Swiss Rhine river (Basel, Switzerland). Master’s thesis. Winterthur: ZHAW Zürcher Hochschule für Angewandte Wissenschaften

Oberhänsli, Silvan. 2023. “Analysis of Bisphenol-A Contamination in Fish Liver and Muscle Tissue : A Method Development and First Assessment of BPA Contamination in Invasive Round Goby Neogobius Melanostomus in the Swiss Rhine River (Basel, Switzerland).” Master’s thesis, Winterthur: ZHAW Zürcher Hochschule für Angewandte Wissenschaften. https://doi.org/10.21256/zhaw-27943.

Oberhänsli, Silvan. Analysis of Bisphenol-A Contamination in Fish Liver and Muscle Tissue : A Method Development and First Assessment of BPA Contamination in Invasive Round Goby Neogobius Melanostomus in the Swiss Rhine River (Basel, Switzerland). ZHAW Zürcher Hochschule für Angewandte Wissenschaften, 2023, https://doi.org/10.21256/zhaw-27943.