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Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-28105
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dc.contributor.authorGong, Liuyu-
dc.contributor.authorBonmarin, Mathias-
dc.contributor.authorSpano, Fabrizio-
dc.contributor.authorShen, Ya-
dc.contributor.authorShen, Lin-
dc.contributor.authorHan, Guocheng-
dc.contributor.authorWei, Shanshan-
dc.contributor.authorZhang, Qihan-
dc.contributor.authorChen, Zhencheng-
dc.contributor.authorZhao, Feijun-
dc.date.accessioned2023-06-22T13:31:29Z-
dc.date.available2023-06-22T13:31:29Z-
dc.date.issued2023-06-15-
dc.identifier.issn1944-8244de_CH
dc.identifier.issn1944-8252de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/28105-
dc.description.abstractThe compositions of sweat and blood are related. Therefore, sweat is an ideal noninvasive test body fluid that could replace blood for linear detection of many biomarkers, especially blood glucose. However, access to sweat samples remains limited to physical exercise, thermal stimulation, or electrical stimulation. Despite intensive research, a continuous, innocuous, and stable method for sweat stimulation and detection has not yet been developed. In this study, a nanomaterial for a sweat-stimulating gel based on the transdermal drug delivery system is presented, which transports acetylcholine chloride into the receptors of sweat glands to achieve the function of biological stimulation of skin sweating. The nanomaterial was applied to a suitable integrated sweat glucose detection device for noninvasive blood glucose monitoring. The total amount of evaporated sweat enabled by the nanomaterial is up to 35 μL·cm-2 for 24 h, and the device detects up to 17.65 μM glucose under optimal conditions, showing stable performance regardless of the user's activity level. In addition, the in vivo test was performed and compared with several studies and products, which showed excellent detection performance and osmotic relationship. The nanomaterial and associated integrated device represent a significant advance in continuous passive sweat stimulation and noninvasive sweat glucose measurement for point-of-care applications.de_CH
dc.language.isoende_CH
dc.publisherAmerican Chemical Societyde_CH
dc.relation.ispartofACS Applied Materials & Interfacesde_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectElectrochemical detectionde_CH
dc.subjectNoninvasive detectionde_CH
dc.subjectSweat detectionde_CH
dc.subjectSweat stimulationde_CH
dc.subjectTransdermal drug delivery systemde_CH
dc.subject.ddc610.28: Biomedizin, Biomedizinische Technikde_CH
dc.subject.ddc660: Technische Chemiede_CH
dc.titleIntegrated device based on a sudomotor nanomaterial for sweat detectionde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementSchool of Engineeringde_CH
zhaw.organisationalunitInstitute of Computational Physics (ICP)de_CH
dc.identifier.doi10.1021/acsami.3c03401de_CH
dc.identifier.doi10.21256/zhaw-28105-
dc.identifier.pmid37318096de_CH
zhaw.funding.euNode_CH
zhaw.issue25de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end29875de_CH
zhaw.pages.start29866de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume15de_CH
zhaw.embargo.end2024-06-15de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.webfeedSensors and Measuring Systemsde_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
Appears in collections:Publikationen School of Engineering

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Gong, L., Bonmarin, M., Spano, F., Shen, Y., Shen, L., Han, G., Wei, S., Zhang, Q., Chen, Z., & Zhao, F. (2023). Integrated device based on a sudomotor nanomaterial for sweat detection. ACS Applied Materials & Interfaces, 15(25), 29866–29875. https://doi.org/10.1021/acsami.3c03401
Gong, L. et al. (2023) ‘Integrated device based on a sudomotor nanomaterial for sweat detection’, ACS Applied Materials & Interfaces, 15(25), pp. 29866–29875. Available at: https://doi.org/10.1021/acsami.3c03401.
L. Gong et al., “Integrated device based on a sudomotor nanomaterial for sweat detection,” ACS Applied Materials & Interfaces, vol. 15, no. 25, pp. 29866–29875, Jun. 2023, doi: 10.1021/acsami.3c03401.
GONG, Liuyu, Mathias BONMARIN, Fabrizio SPANO, Ya SHEN, Lin SHEN, Guocheng HAN, Shanshan WEI, Qihan ZHANG, Zhencheng CHEN und Feijun ZHAO, 2023. Integrated device based on a sudomotor nanomaterial for sweat detection. ACS Applied Materials & Interfaces. 15 Juni 2023. Bd. 15, Nr. 25, S. 29866–29875. DOI 10.1021/acsami.3c03401
Gong, Liuyu, Mathias Bonmarin, Fabrizio Spano, Ya Shen, Lin Shen, Guocheng Han, Shanshan Wei, Qihan Zhang, Zhencheng Chen, and Feijun Zhao. 2023. “Integrated Device Based on a Sudomotor Nanomaterial for Sweat Detection.” ACS Applied Materials & Interfaces 15 (25): 29866–75. https://doi.org/10.1021/acsami.3c03401.
Gong, Liuyu, et al. “Integrated Device Based on a Sudomotor Nanomaterial for Sweat Detection.” ACS Applied Materials & Interfaces, vol. 15, no. 25, June 2023, pp. 29866–75, https://doi.org/10.1021/acsami.3c03401.


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