Please use this identifier to cite or link to this item:
https://doi.org/10.21256/zhaw-28377
Publication type: | Article in scientific journal |
Type of review: | Peer review (publication) |
Title: | Predictive validity of the Hand Assessment for Infants in infants at risk of unilateral cerebral palsy |
Authors: | Ryll, Ulrike C. Krumlinde-Sundholm, Lena Verhage, Cornelia H. Sicola, Elisa Sgandurra, Giuseppina Bastiaenen, Caroline H. G. Eliasson, Ann-Christin |
et. al: | No |
DOI: | 10.1111/dmcn.14739 10.21256/zhaw-28377 |
Published in: | Developmental Medicine & Child Neurology |
Volume(Issue): | 63 |
Issue: | 4 |
Page(s): | 436 |
Pages to: | 443 |
Issue Date: | 29-Nov-2020 |
Publisher / Ed. Institution: | Wiley |
ISSN: | 1469-8749 |
Language: | English |
Subjects: | Cerebral palsy; Hand; Infant; Mass screening; Sensitivity and specificity; Disability evaluation |
Subject (DDC): | 616.8: Neurology, diseases of nervous system 618.92: Pediatrics |
Abstract: | Aim: To evaluate the sensitivity, specificity, and predictive value of the Hand Assessment for Infants (HAI) in identifying infants at risk of being diagnosed with unilateral cerebral palsy(CP), and to determine cut-off values for this purpose. Method: A convenience sample of 203 infants (106 females, 97 males) was assessed by the HAI at 3, 6, 9, and 12 months. Sensitivity, specificity, predictive values, and likelihood ratios were calculated using receiver operating characteristic curve analysis. Cut-off values were derived for different ages. The clinical outcome (unilateral CP yes/no) at 24 months or more served as an external criterion to investigate the predictive validity of HAI. Results: Half of the infants developed unilateral CP. The area under the curve ranged from0.77 (95% CI [confidence interval] 0.63–0.91) to 0.95 (95% CI 0.90–1.00) across HAI scales and age intervals. Likewise, sensitivity ranged from 63% to 93%, specificity from 62% to 91%, and accuracy from 73% to 94%. Interpretation: HAI scores demonstrated overall accuracy that ranged from very good to excellent in predicting unilateral CP in infants at risk aged between 3.5 and 12 months. This accuracy increased with age at assessment and the earliest possible prediction was at3.5 months of age, when appropriate HAI cut-off values for different ages were applied. |
URI: | https://digitalcollection.zhaw.ch/handle/11475/28377 |
Fulltext version: | Published version |
License (according to publishing contract): | CC BY-NC-ND 4.0: Attribution - Non commercial - No derivatives 4.0 International |
Departement: | School of Health Sciences |
Appears in collections: | Publikationen Gesundheit |
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Ryll, U. C., Krumlinde-Sundholm, L., Verhage, C. H., Sicola, E., Sgandurra, G., Bastiaenen, C. H. G., & Eliasson, A.-C. (2020). Predictive validity of the Hand Assessment for Infants in infants at risk of unilateral cerebral palsy. Developmental Medicine & Child Neurology, 63(4), 436–443. https://doi.org/10.1111/dmcn.14739
Ryll, U.C. et al. (2020) ‘Predictive validity of the Hand Assessment for Infants in infants at risk of unilateral cerebral palsy’, Developmental Medicine & Child Neurology, 63(4), pp. 436–443. Available at: https://doi.org/10.1111/dmcn.14739.
U. C. Ryll et al., “Predictive validity of the Hand Assessment for Infants in infants at risk of unilateral cerebral palsy,” Developmental Medicine & Child Neurology, vol. 63, no. 4, pp. 436–443, Nov. 2020, doi: 10.1111/dmcn.14739.
RYLL, Ulrike C., Lena KRUMLINDE-SUNDHOLM, Cornelia H. VERHAGE, Elisa SICOLA, Giuseppina SGANDURRA, Caroline H. G. BASTIAENEN und Ann-Christin ELIASSON, 2020. Predictive validity of the Hand Assessment for Infants in infants at risk of unilateral cerebral palsy. Developmental Medicine & Child Neurology. 29 November 2020. Bd. 63, Nr. 4, S. 436–443. DOI 10.1111/dmcn.14739
Ryll, Ulrike C., Lena Krumlinde-Sundholm, Cornelia H. Verhage, Elisa Sicola, Giuseppina Sgandurra, Caroline H. G. Bastiaenen, and Ann-Christin Eliasson. 2020. “Predictive Validity of the Hand Assessment for Infants in Infants at Risk of Unilateral Cerebral Palsy.” Developmental Medicine & Child Neurology 63 (4): 436–43. https://doi.org/10.1111/dmcn.14739.
Ryll, Ulrike C., et al. “Predictive Validity of the Hand Assessment for Infants in Infants at Risk of Unilateral Cerebral Palsy.” Developmental Medicine & Child Neurology, vol. 63, no. 4, Nov. 2020, pp. 436–43, https://doi.org/10.1111/dmcn.14739.
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