To what degree patient-reported symptoms of central sensitization, kinesiophobia, disability, sleep, and life quality associated with 24-h heart rate variability and actigraphy measurements?

Mikkonen, Jani; Kupari, Saana; Tarvainen, Mika; Neblett, Randy; Airaksinen, Olavi; Luomajoki, Hannu; Leinonen, Ville

doi:10.1111/papr.13331

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-29428

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	To what degree patient-reported symptoms of central sensitization, kinesiophobia, disability, sleep, and life quality associated with 24-h heart rate variability and actigraphy measurements?
Authors:	Mikkonen, Jani Kupari, Saana Tarvainen, Mika Neblett, Randy Airaksinen, Olavi Luomajoki, Hannu Leinonen, Ville
et. al:	No
DOI:	10.1111/papr.13331 10.21256/zhaw-29428
Published in:	Pain Practice
Issue Date:	12-Dec-2023
Publisher / Ed. Institution:	Wiley
ISSN:	1530-7085 1533-2500
Language:	English
Subjects:	Actigraphy; Breathing rate; Central sensitization; Chronic musculoskeletal pain; Heart rate variability; Kinesiophobia; Patient-reported outcome measure; Sleep quality
Subject (DDC):	616.7: Diseases of musculoskeletal system and orthopaedics
Abstract:	Objectives: Chronic musculoskeletal pain is associated with decreased parasympathetic and increased sympathetic activity in the autonomic nervous system. The objective of this study was to determine the associations between objective measures of heart rate variability (a measure of autonomic nervous system function), actigraphy (a measure of activity and sleep quality), respiration rates, and subjective patient-reported outcome measures (PROMs) of central sensitization, kinesiophobia, disability, the effect of pain on sleep, and life quality. Methods: Thirty-eight study subjects were divided into two subgroups, including low symptoms of central sensitization (n = 18) and high symptoms of central sensitization (n = 20), based on patient-reported scores on the Central Sensitization Inventory (CSI). Heart rate variability (HRV) and actigraphy measurements were carried out simultaneously in 24 h measurement during wakefulness and sleep. Results: A decrease in HRV during the first 2 h of sleep was stronger in the low CSI subgroup compared to the high CSI subgroup. Otherwise, all other HRV and actigraphy parameters and subjective measures of central sensitization, disability, kinesiophobia, the effect of pain on sleep, and quality of life showed only little associations. Discussion: The high CSI subgroup reported significantly more severe symptoms of disability, kinesiophobia, sleep, and quality of life compared to the low CSI subgroup. However, there were only small and nonsignificant trend in increased sympathetic nervous system activity and poorer sleep quality on the high central sensitization subgroup. Moreover, very little differences in respiratory rates were found between the groups.
URI:	https://digitalcollection.zhaw.ch/handle/11475/29428
Fulltext version:	Published version
License (according to publishing contract):	CC BY 4.0: Attribution 4.0 International
Departement:	School of Health Sciences
Organisational Unit:	Institute of Physiotherapy (IPT)
Appears in collections:	Publikationen Gesundheit

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Mikkonen, J., Kupari, S., Tarvainen, M., Neblett, R., Airaksinen, O., Luomajoki, H., & Leinonen, V. (2023). To what degree patient-reported symptoms of central sensitization, kinesiophobia, disability, sleep, and life quality associated with 24-h heart rate variability and actigraphy measurements? Pain Practice. https://doi.org/10.1111/papr.13331

Mikkonen, J. et al. (2023) ‘To what degree patient-reported symptoms of central sensitization, kinesiophobia, disability, sleep, and life quality associated with 24-h heart rate variability and actigraphy measurements?’, Pain Practice [Preprint]. Available at: https://doi.org/10.1111/papr.13331.

J. Mikkonen et al., “To what degree patient-reported symptoms of central sensitization, kinesiophobia, disability, sleep, and life quality associated with 24-h heart rate variability and actigraphy measurements?,” Pain Practice, Dec. 2023, doi: 10.1111/papr.13331.

MIKKONEN, Jani, Saana KUPARI, Mika TARVAINEN, Randy NEBLETT, Olavi AIRAKSINEN, Hannu LUOMAJOKI und Ville LEINONEN, 2023. To what degree patient-reported symptoms of central sensitization, kinesiophobia, disability, sleep, and life quality associated with 24-h heart rate variability and actigraphy measurements? Pain Practice. 12 Dezember 2023. DOI 10.1111/papr.13331

Mikkonen, Jani, Saana Kupari, Mika Tarvainen, Randy Neblett, Olavi Airaksinen, Hannu Luomajoki, and Ville Leinonen. 2023. “To What Degree Patient-Reported Symptoms of Central Sensitization, Kinesiophobia, Disability, Sleep, and Life Quality Associated with 24-H Heart Rate Variability and Actigraphy Measurements?” Pain Practice, December. https://doi.org/10.1111/papr.13331.

Mikkonen, Jani, et al. “To What Degree Patient-Reported Symptoms of Central Sensitization, Kinesiophobia, Disability, Sleep, and Life Quality Associated with 24-H Heart Rate Variability and Actigraphy Measurements?” Pain Practice, Dec. 2023, https://doi.org/10.1111/papr.13331.