Effects of hand-training in persons with myotonic dystrophy type 1 : a randomised controlled cross-over pilot study

Aldehag, Anna; Jonsson, Hans; Lindblad, Jan; Kottorp, Anders; Ansved, Tor; Kierkegaard, Marie

doi:10.3109/09638288.2012.754952

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Effects of hand-training in persons with myotonic dystrophy type 1 : a randomised controlled cross-over pilot study
Authors:	Aldehag, Anna Jonsson, Hans Lindblad, Jan Kottorp, Anders Ansved, Tor Kierkegaard, Marie
DOI:	10.3109/09638288.2012.754952
Published in:	Disability and Rehabilitation
Volume(Issue):	35
Issue:	21
Page(s):	1798
Pages to:	1807
Issue Date:	2013
Publisher / Ed. Institution:	Taylor & Francis
ISSN:	0963-8288 1464-5165
Language:	English
Subjects:	Cross-over study; Disability evaluation; Muscle weakness; Myotonic dystrophy; Occupational therapy; Severity of Illness Index
Subject (DDC):	616.7: Diseases of musculoskeletal system and orthopaedics
Abstract:	Purpose: To investigate the effects of a hand-training programme on grip, pinch and wrist force, manual dexterity and activities of daily living, in adults with myotonic dystrophy type 1 (DM1). Method: In this randomised controlled trial with a crossover design, 35 adults with DM1 were, after stratification for grip force, assigned by lot to two groups. Group A started with 12 weeks of hand training, while group B had no intervention. After a wash-out period of 12 weeks, where none received training, the order was reversed. The Grippit® was used as primary outcome measure and the hand-held Microfet2™ myometer, the Purdue Pegboard, the Canadian Occupational Performance Measure (COPM) and the Assessment of Motor and Process Skills (AMPS) were secondary outcome measures. Assessments were performed before and after training and control periods, i.e. four times altogether. Results: Ten persons dropped out and 13 had acceptable adherence. Intention-to-treat analyses revealed significant intervention effects for isometric wrist flexor force (p = 0.048), and for COPM performance (p = 0.047) and satisfaction (p = 0.027). On an individual level, improvements were in general showed after a training period. Conclusion: The hand-training programme had positive effects on wrist flexor force and self-perception of occupational performance, and of satisfaction with performance. No evident detrimental effects were shown.
URI:	https://digitalcollection.zhaw.ch/handle/11475/8702
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	School of Health Sciences
Organisational Unit:	Institute of Occupational Therapy (IER)
Appears in collections:	Publikationen Gesundheit

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Aldehag, A., Jonsson, H., Lindblad, J., Kottorp, A., Ansved, T., & Kierkegaard, M. (2013). Effects of hand-training in persons with myotonic dystrophy type 1 : a randomised controlled cross-over pilot study. Disability and Rehabilitation, 35(21), 1798–1807. https://doi.org/10.3109/09638288.2012.754952

Aldehag, A. et al. (2013) ‘Effects of hand-training in persons with myotonic dystrophy type 1 : a randomised controlled cross-over pilot study’, Disability and Rehabilitation, 35(21), pp. 1798–1807. Available at: https://doi.org/10.3109/09638288.2012.754952.

A. Aldehag, H. Jonsson, J. Lindblad, A. Kottorp, T. Ansved, and M. Kierkegaard, “Effects of hand-training in persons with myotonic dystrophy type 1 : a randomised controlled cross-over pilot study,” Disability and Rehabilitation, vol. 35, no. 21, pp. 1798–1807, 2013, doi: 10.3109/09638288.2012.754952.

ALDEHAG, Anna, Hans JONSSON, Jan LINDBLAD, Anders KOTTORP, Tor ANSVED und Marie KIERKEGAARD, 2013. Effects of hand-training in persons with myotonic dystrophy type 1 : a randomised controlled cross-over pilot study. Disability and Rehabilitation. 2013. Bd. 35, Nr. 21, S. 1798–1807. DOI 10.3109/09638288.2012.754952

Aldehag, Anna, Hans Jonsson, Jan Lindblad, Anders Kottorp, Tor Ansved, and Marie Kierkegaard. 2013. “Effects of Hand-Training in Persons with Myotonic Dystrophy Type 1 : A Randomised Controlled Cross-over Pilot Study.” Disability and Rehabilitation 35 (21): 1798–1807. https://doi.org/10.3109/09638288.2012.754952.

Aldehag, Anna, et al. “Effects of Hand-Training in Persons with Myotonic Dystrophy Type 1 : A Randomised Controlled Cross-over Pilot Study.” Disability and Rehabilitation, vol. 35, no. 21, 2013, pp. 1798–807, https://doi.org/10.3109/09638288.2012.754952.