Please use this identifier to cite or link to this item:
https://doi.org/10.21256/zhaw-5505
Publication type: | Article in scientific journal |
Type of review: | Peer review (publication) |
Title: | Non-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cells |
Authors: | Jonsdottir, Hulda R. Delaval, Mathilde Leni, Zaira Keller, Alejandro Brem, Benjamin T. Siegerist, Frithjof Schönenberger, David Durdina, Lukas Elser, Miriam Burtscher, Heinz Liati, Anthi Geiser, Marianne |
DOI: | 10.21256/zhaw-5505 10.1038/s42003-019-0332-7 |
Published in: | Communications Biology |
Volume(Issue): | 2 |
Issue: | 90 |
Issue Date: | 2019 |
Publisher / Ed. Institution: | Nature Publishing Group |
ISSN: | 2399-3642 |
Language: | English |
Subjects: | Mechanisms of disease; Respiratory tract diseases |
Subject (DDC): | 363: Environmental and security problems |
Abstract: | Aircraft emissions contribute to local and global air pollution. Health effects of particulate matter (PM) from aircraft engines are largely unknown, since controlled cell exposures at relevant conditions are challenging. We examined the toxicity of non-volatile PM (nvPM) emissions from a CFM56-7B26 turbofan, the world's most used aircraft turbine using an unprecedented exposure setup. We combined direct turbine-exhaust sampling under realistic engine operating conditions and the Nano-Aerosol Chamber for In vitro Toxicity to deposit particles onto air-liquid-interface cultures of human bronchial epithelial cells (BEAS-2B) at physiological conditions. We evaluated acute cellular responses after 1-h exposures to diluted exhaust from conventional or alternative fuel combustion. We show that single, short-term exposures to nvPM impair bronchial epithelial cells, and PM from conventional fuel at ground-idle conditions is the most hazardous. Electron microscopy of soot reveals varying reactivity matching the observed cellular responses. Stronger responses at lower mass concentrations suggest that additional metrics are necessary to evaluate health risks of this increasingly important emission source. |
URI: | https://digitalcollection.zhaw.ch/handle/11475/16116 |
Fulltext version: | Published version |
License (according to publishing contract): | CC BY 4.0: Attribution 4.0 International |
Departement: | School of Engineering |
Organisational Unit: | Centre for Aviation (ZAV) |
Appears in collections: | Publikationen School of Engineering |
Files in This Item:
File | Description | Size | Format | |
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s42003-019-0332-7.pdf | published PDF | 1.52 MB | Adobe PDF | View/Open |
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Jonsdottir, H. R., Delaval, M., Leni, Z., Keller, A., Brem, B. T., Siegerist, F., Schönenberger, D., Durdina, L., Elser, M., Burtscher, H., Liati, A., & Geiser, M. (2019). Non-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cells. Communications Biology, 2(90). https://doi.org/10.21256/zhaw-5505
Jonsdottir, H.R. et al. (2019) ‘Non-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cells’, Communications Biology, 2(90). Available at: https://doi.org/10.21256/zhaw-5505.
H. R. Jonsdottir et al., “Non-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cells,” Communications Biology, vol. 2, no. 90, 2019, doi: 10.21256/zhaw-5505.
JONSDOTTIR, Hulda R., Mathilde DELAVAL, Zaira LENI, Alejandro KELLER, Benjamin T. BREM, Frithjof SIEGERIST, David SCHÖNENBERGER, Lukas DURDINA, Miriam ELSER, Heinz BURTSCHER, Anthi LIATI und Marianne GEISER, 2019. Non-volatile particle emissions from aircraft turbine engines at ground-idle induce oxidative stress in bronchial cells. Communications Biology. 2019. Bd. 2, Nr. 90. DOI 10.21256/zhaw-5505
Jonsdottir, Hulda R., Mathilde Delaval, Zaira Leni, Alejandro Keller, Benjamin T. Brem, Frithjof Siegerist, David Schönenberger, et al. 2019. “Non-Volatile Particle Emissions from Aircraft Turbine Engines at Ground-Idle Induce Oxidative Stress in Bronchial Cells.” Communications Biology 2 (90). https://doi.org/10.21256/zhaw-5505.
Jonsdottir, Hulda R., et al. “Non-Volatile Particle Emissions from Aircraft Turbine Engines at Ground-Idle Induce Oxidative Stress in Bronchial Cells.” Communications Biology, vol. 2, no. 90, 2019, https://doi.org/10.21256/zhaw-5505.
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